May 29, 2017
Recommended Topic Related To:

Lodine

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Lodine

Discontinued Warning IconPlease Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)




Indications
Dosage
How Supplied

INDICATIONS

Carefully consider the potential benefits and risks of etodolac capsules and other treatment options before deciding to use etodolac capsules. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals (see WARNINGS).

Etodolac capsules are indicated:

  • For acute and long-term use in the management of signs and symptoms of the following:
  1. Osteoarthritis
  2. Rheumatoid arthritis

DOSAGE AND ADMINISTRATION

Carefully consider the potential benefits and risks of etodolac capsules and other treatment options before deciding to use etodolac capsules. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals (see WARNINGS).

After observing the response to initial therapy with etodolac capsules, the dose and frequency should be adjusted to suit an individual patient's needs.

Dosage adjustment of etodolac capsules is generally not required in patients with mild to moderate renal impairment. Etodolac capsules should be used with caution in such patients, because, as with other NSAIDs, they may further decrease renal function in some patients with impaired renal function (see WARNINGS, Renal Effects ).

Analgesia

The recommended total daily dose of etodolac capsules for acute pain is up to 1000 mg, given as 200 to 400 mg every 6 to 8 hours. Doses of etodolac greater than 1000 mg/day have not been adequately evaluated in well-controlled clinical trials.

Osteoarthritis And Rheumatoid Arthritis

The recommended starting dose of etodolac capsules for the management of the signs and symptoms of osteoarthritis or rheumatoid arthritis is: 300 mg b.i.d., t.i.d., or 400 mg b.i.d., or 500 mg b.i.d. A lower dose of 600 mg/day may suffice for long-term administration. Physicians should be aware that doses above 1000 mg/day have not been adequately evaluated in well-controlled clinical trials.

In chronic conditions, a therapeutic response to therapy with etodolac capsules is sometimes seen within one week of therapy, but most often is observed by two weeks. After a satisfactory response has been achieved, the patient's dose should be reviewed and adjusted as required.

HOW SUPPLIED

Etodolac capsules USP, 300 mg are available as opaque, dark red body and cap, hard gelatin capsules supplied as

NDC 63629-1376-1 bottles of 20
NDC 63629-1376-2 bottles of 60
NDC
63629-1376-3 bottles of 30
NDC
63629-1376-4 bottles of 45
NDC
63629-1376-5 bottles of 42
NDC
63629-1376-6 bottles of 120
NDC
63629-1376-7 bottles of 90
NDC
63629-1376-8 bottles of 25
NDC
63629-1376-9 bottles of 21

Store at 20° to 25°C (68° to 77°F) [See USP Controlled Room Temperature], protected from moisture.

Dispense in a tight, light-resistant container as defined in the USP, with a child-resistant closure (as required). Keep container tightly closed.

Manufactured In Canada By: NOVOPHARM LIMITED, Toronto, Canada M1B 2K9. Distributed by: Bryant Ranch Prepack, 12623 Sherman Way, North Hollywood, CA 91605. Voice (877) 885-0882 Fax (877) 277-7552. Revised: Oct 2012

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 9/13/2016

Indications
Dosage
How Supplied

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