"Nov. 6, 2012 -- The FDA has approved Pfizer's Xeljanz (tofacitinib), a first-of-its-kind treatment for rheumatoid arthritis.
Xeljanz is approved for use by patients not helped by methotrexate, the usual first treatment for RA. It's a "...
(Generic versions may still be available.)
- Clinician Information:
Lodine Patient Information including How Should I Take
In this Article
- What is etodolac (Lodine)?
- What are the possible side effects of etodolac (Lodine)?
- What is the most important information I should know about etodolac (Lodine)?
- What should I discuss with my healthcare provider before taking etodolac (Lodine)?
- How should I take etodolac (Lodine)?
- What happens if I miss a dose (Lodine)?
- What happens if I overdose (Lodine)?
- What should I avoid while taking etodolac (Lodine)?
- What other drugs will affect etodolac (Lodine)?
- Where can I get more information?
What should I discuss with my healthcare provider before taking etodolac (Lodine)?
Taking an NSAID can increase your risk of life-threatening heart or circulation problems, including heart attack or stroke. This risk will increase the longer you use an NSAID. Do not use this medicine just before or after having heart bypass surgery (also called coronary artery bypass graft, or CABG).
NSAIDs can also increase your risk of serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and gastrointestinal effects can occur without warning at any time while you are taking an NSAID. Older adults may have an even greater risk of these serious gastrointestinal side effects.
Do not use this medication if you are allergic to etodolac, or if you have a history of allergic reaction to aspirin or other NSAIDs.
Before taking etodolac, tell your doctor if you are allergic to any drugs, or if you have:
- a history of heart attack, stroke, or blood clot;
- heart disease, congestive heart failure, high blood pressure;
- a history of stomach ulcers or bleeding;
- liver or kidney disease,
- polyps in your nose;
- a bleeding or blood clotting disorder; or
- if you smoke.
If you have any of these conditions, you may need a dose adjustment or special tests to safely take etodolac.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Taking etodolac during the last 3 months of pregnancy may harm the unborn baby. Do not take etodolac during pregnancy unless your doctor has told you to.
It is not known whether etodolac passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Do not give this medicine to a child younger than 6 years old without the advice of a doctor.
How should I take etodolac (Lodine)?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.
It may take up to 2 weeks of using this medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve.
If you take etodolac for a long period of time, your doctor may want to check you on a regular basis to make sure this medication is not causing harmful effects. Do not miss any scheduled visits to your doctor.
This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using etodolac.
Store etodolac at room temperature away from moisture and heat.
Additional Lodine Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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