"What are NSAIDs and how do they work?
As the class name suggests, nonsteroidal antiinflammatory drugs (NSAIDs) reduce inflammation but are not related to steroids which also reduce inflammation. NSAIDs work by reducing the productio"...
(Generic versions may still be available.)
- Clinician Information:
Lodine Patient Information Including Side Effects
Brand Names: Lodine, Lodine XL
Generic Name: etodolac (Pronunciation: ee toe DOE lak)
- What is etodolac (Lodine)?
- What are the possible side effects of etodolac (Lodine)?
- What is the most important information I should know about etodolac (Lodine)?
- What should I discuss with my healthcare provider before taking etodolac (Lodine)?
- How should I take etodolac (Lodine)?
- What happens if I miss a dose (Lodine)?
- What happens if I overdose (Lodine)?
- What should I avoid while taking etodolac (Lodine)?
- What other drugs will affect etodolac (Lodine)?
- Where can I get more information?
What is etodolac (Lodine)?
Etodolac is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Etodolac works by reducing hormones that cause inflammation and pain in the body.
Etodolac is used to treat pain or inflammation caused by arthritis.
Etodolac may also be used for other purposes not listed in this medication guide.
Etodolac 200 mg-APO
gray/white, imprinted with APO, 039
Etodolac 200 mg-ESI
white, imprinted with 59911 3606, 200
Etodolac 200 mg-TAR
pink, imprinted with ETO 200 MG
Etodolac 300 mg-APO
gray/white, imprinted with APO, 040
Etodolac 300 mg-ESI
white, imprinted with 59911 3607, 300
Etodolac 300 mg-TAR
pink, imprinted with ETO 300 MG
Etodolac 300 mg-TEV
red, imprinted with N 397 300, striped
Etodolac 400 mg ER-TEV
oblong, orange, imprinted with 93, 1122
Etodolac 400 mg-APO
oblong, white, imprinted with 400, APO 041
Etodolac 400 mg-ESI
oblong, white, imprinted with 59911, 3608
Etodolac 400 mg-TAR
oblong, peach, imprinted with T 88
Etodolac 400 mg-TEV
oblong, pink, imprinted with 93, 892
Etodolac 500 mg ER-TEV
oblong, gray, imprinted with 93, 7172
Etodolac 500 mg-EON
oval, white, imprinted with E139
Etodolac 500 mg-PAR
oval, blue, imprinted with G, ET 500
Etodolac 500 mg-TAR
oblong, green, imprinted with T500
Etodolac 500 mg-TEV
oval, blue, imprinted with 93, 1893
Etodolac 600 mg ER-TEV
oblong, blue, imprinted with 93, 1118
Etodolac ER 400 mg-TAR
round, pink, imprinted with T400
Etodolac ER 500 mg-TAR
oblong, green, imprinted with T500
Etodolac ER 600 mg-TAR
oval, gray, imprinted with T600
Lodine 300 mg
gray, imprinted with LODINE 300
Lodine 400 mg
oblong, orange, imprinted with LODINE 400
Lodine XL 500 mg
oval, green, imprinted with LODINE XL 500
What are the possible side effects of etodolac (Lodine)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking etodolac and seek medical attention or call your doctor at once if you have any of these serious side effects:
- chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance;
- black, bloody, or tarry stools;
- coughing up blood or vomit that looks like coffee grounds;
- swelling or rapid weight gain;
- urinating less than usual or not at all;
- nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
- fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
- bruising, severe tingling, numbness, pain, muscle weakness; or
- fever, headache, neck stiffness, chills, increased sensitivity to light, purple spots on the skin, and/or seizure (convulsions).
Less serious side effects may include:
- upset stomach, mild heartburn or stomach pain, diarrhea, constipation;
- bloating, gas;
- dizziness, headache, nervousness;
- skin itching or rash;
- sore throat, stuffy nose;
- blurred vision; or
- ringing in your ears.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Read the Lodine (etodolac) Side Effects Center for a complete guide to possible side effects
What is the most important information I should know about etodolac (Lodine)?
This medicine can increase your risk of life-threatening heart or circulation problems, including heart attack or stroke. This risk will increase the longer you use etodolac. Do not use this medicine just before or after having heart bypass surgery (also called coronary artery bypass graft, or CABG).
Seek emergency medical help if you have symptoms of heart or circulation problems, such as chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance.
This medicine can also increase your risk of serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and gastrointestinal effects can occur without warning at any time while you are taking etodolac. Older adults may have an even greater risk of these serious gastrointestinal side effects.
Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds.
Do not use any other over-the-counter cold, allergy, or pain medication without first asking your doctor or pharmacist. Many medicines available over the counter contain aspirin or other medicines similar to etodolac (such as ibuprofen, ketoprofen, or naproxen). If you take certain products together you may accidentally take too much of this type of medication. Read the label of any other medicine you are using to see if it contains aspirin, ibuprofen, ketoprofen, or naproxen.
Do not drink alcohol while taking etodolac. Alcohol can increase the risk of stomach bleeding caused by etodolac.
Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Etodolac can make your skin more sensitive to sunlight and sunburn may result.
Additional Lodine Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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