Lodosyn (Carbidopa) Patient Information: Missed a Dose and What Should I Avoid at RxList

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May 27, 2012

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Parkinson's disease is the second most common neurodegenerative disorder and the most common movement disorder. It is characterized by progressive loss of muscle control, which leads to trembling of the limbs and head while at rest, stiffness, slowness, and impaired balance. As symptoms worsen, it may become difficult to walk, talk, and complete simple tasks.

The progression of Parkinson's disease and the degree of impairment vary from individual to individual. Many people with Parkinson's disease live long productive lives, whereas others become disabled much more quickly. Premature death is usually due to complications such as falling-related injuries or pneumonia.

In the United States, about 1 million people are affected by Parkinson's disease and worldwide about 5 million. Most individuals who develop Parkinson's disease are 60 years of age or older. Parkinson's disease occurs in approximately 1% of i...

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Lodosyn Patient Information including If I Miss a Dose

What happens if I miss a dose (Lodosyn)?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and only take the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose (Lodosyn)?

Seek emergency medical attention if an overdose is suspected.

Symptoms of a carbidopa overdose include muscle spasms or weakness, spasms of the eyelid, nausea, vomiting, diarrhea, an irregular heartbeat, confusion, agitation, hallucinations, and unconsciousness.

What should I avoid while taking carbidopa (Lodosyn)?

Use caution when driving, operating machinery, or performing other hazardous activities. Carbidopa may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

What other drugs will affect carbidopa (Lodosyn)?

Do not take carbidopa and levodopa if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the past 14 days.

Antacids may increase the effectiveness of carbidopa and levodopa and lead to side effects. Ask your doctor about the use of antacids.

Before taking carbidopa, tell your doctor if you are taking any of the following medicines:

a medicine to treat high blood pressure (hypertension);
a medicine used to treat seizures, such as phenytoin (Dilantin), ethotoin (Peganone), or mephenytoin (Mesantoin);
papaverine (Pavabid, Cerespan, others);
pyridoxine or vitamin B6;
an antidepressant such as amitriptyline (Elavil), doxepin (Sinequan), nortriptyline (Pamelor), desipramine (Norpramin), and amoxapine (Asendin); or
a medicine used to treat a psychiatric condition (or nausea and vomiting), such as chlorpromazine (Thorazine), fluphenazine (Prolixin), mesoridazine (Serentil), thioridazine (Mellaril), trifluoperazine (Stelazine), and haloperidol (Haldol).

You may not be able to take carbidopa, or you may require a dosage adjustment or special monitoring if you are taking any of the medicines listed above.

Levodopa may interfere with urine tests for sugar and ketones. If you have diabetes and notice changes in urine test results, talk to your doctor before making any changes in your diabetes medication.

Drugs other than those listed here may also interact with carbidopa. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

Your pharmacist can provide more information about carbidopa.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed

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