July 27, 2016
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Lok Pak

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Lok Pak

Lok Pak Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 5/20/2016

Lok Pak (heparin lock flush solution) is used only to maintain potency of an intravenous injection device. Lok Pak may be used following initial placement of the device in the vein, after each injection of a medication or after withdrawal of blood for laboratory analysis. The Lok Pak solution is not to be used for anticoagulation therapy. Lok Pak may be available in generic form. Side effects of Lok Pak are uncommon; consult your doctor.

Lok Pak Heparin Lock Flush Solution 10 or 100 USP Units/mL, is injected as a single dose into an intravenous injection device using a volume of solution equivalent to that of the indwelling venipuncture device. Lok Pak may interact with oral anticoagulants, acetylsalicylic acid, dextran, phenylbutazone, ibuprofen, indomethacin, dipyridamole, hydroxychloroquine, digitalis, tetracyclines, nicotine, antihistamines, or I.V. nitroglycerin. Tell your doctor all medications and supplements you use. During pregnancy, Lok Pak Heparin Lock Flush Solution should be used only if prescribed. This drug does not pass into breast milk. Consult your doctor before breastfeeding.

Our Lok Pak (heparin lock flush solution) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Lok Pak FDA Prescribing Information: Side Effects
(Adverse Reactions)


Although adverse reactions to intravenous intramuscular or subcutaneous injection of 0.9% benzyl alcohol are not known to occur in man, experimental studies of small volume parenteral preparations containing 0.9% benzyl alcohol in several species of animals have indicated that an estimated intravenous dose up to 30 mL may be safely given to an adult without toxic effects. Administration of an estimated 9 mL to 6 kg infant is potentially capable of producing blood pressure changes.

Heparin Lock Flush Solution is not known to cause adverse local or systemic effects of any kind. Although a remote possibility of hypersensitivity reaction exists with entry of extremely small subtherapeutic amounts of the solution into the circulation, such an occurrence has not been reported.

Read the entire FDA prescribing information for Lok Pak (Heparin Lock Flush Solution)

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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