Lomotil (Diphenoxylate and Atropine) Drug Information: Medication Guide and Patient Information

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May 27, 2012

Lomotil

Diarrhea »

Diarrhea facts

Diarrhea is an increase in the frequency of bowel movements, an increase in the looseness of stool or both.
Diarrhea is caused by increased secretion of fluid into the intestine, reduced absorption of fluid from the intestine or rapid passage of stool through the intestine.
Diarrhea can be defined absolutely or relatively. Absolute diarrhea is defined as more than five bowel movements a day or liquid stools. Relative diarrhea is defined as an increase in the number of bowel movements per day or an increase in the looseness of stools compared with an individual's usual bowel habit.
Diarrhea may be either acute or chronic, and each has different causes and treatments.
Complications of diarrhea include dehydration, electrolytes (mineral) abnormalities, and irritation of the anus.
Dehydration can be treated with oral ...

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PATIENT INFORMATION

INFORM THE PATIENT (PARENT OR GUARDIAN) NOT TO EXCEED THE RECOMMENDED DOSAGE AND TO KEEP LOMOTIL (diphenoxylate and atropine) OUT OF THE REACH OF CHILDREN AND IN A CHILD-RESISTANT CONTAINER. INFORM THE PATIENT OF THE CONSEQUENCES OF OVERDOSAGE, INCLUDING SEVERE RESPIRATORY DEPRESSION AND COMA, POSSIBLY LEADING TO PERMANENT BRAIN DAMAGE OR DEATH. Lomotil (diphenoxylate and atropine) may produce drowsiness or dizziness. The patient should be cautioned regarding activities requiring mental alertness, such as driving or operating dangerous machinery. Potentiation of the action of alcohol, barbiturates, and tranquilizers with concomitant use of Lomotil (diphenoxylate and atropine) should be explained to the patient. The physician should also provide the patient with other information in this labeling, as appropriate.

Last reviewed on RxList: 10/4/2010
This monograph has been modified to include the generic and brand name in many instances.