"The U.S. Food and Drug Administration today approved Kynamro (mipomersen sodium) injection as an addition to lipid-lowering medications and diet to treat patients with a rare type of high cholesterol called homozygous familial hypercholesterolemi"...
There have been reported cases of overdosage with LOPID. In one case, a 7-year-old child recovered after ingesting up to 9 grams of LOPID. Symptoms reported with overdosage were abdominal cramps, abnormal liver function tests, diarrhea, increased CPK, joint and muscle pain, nausea and vomiting. Symptomatic supportive measures should be taken, should an overdose occur.
- Hepatic or severe renal dysfunction, including primary biliary cirrhosis.
- Preexisting gallbladder disease (see WARNINGS).
- Hypersensitivity to gemfibrozil.
- Combination therapy of gemfibrozil with repaglinide (see PRECAUTIONS).
- Combination therapy of gemfibrozil with simvastatin (see WARNINGS and PRECAUTIONS).
Last reviewed on RxList: 11/13/2014
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