Lopressor HCT (Metoprolol Tartrate and Hydochlorothiazide) Drug Information: Medication Guide and Patient Information

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May 27, 2012

Lopressor HCT

Calcium Channel Blockers (CCBs) »

What are calcium channel blockers (CCBs) and how do they work?

Calcium channel blockers are drugs that block the entry of calcium into the muscle cells of the heart and arteries.

The entry of calcium is critical for the conduction of the electrical signal that passes from muscle cell to muscle cell of the heart, and signals the cells to contract.
It also is necessary in order for the muscle cells to contract and thereby pump blood.
In the arteries, the entry of calcium into muscle cells causes contraction of the cells and thereby dilates (widens) the arteries.
Thus, by blocking the entry of calcium, calcium channel blockers reduce electrical conduction within the heart, decrease the force of contraction (work) of the muscle cells, and dilate arteries.
Dilation of the arteries reduces blood pressure and thereby the effort the heart must exert to pump blood.
Combined with decr...

Read the Calcium Channel Blockers (CCBs) article »

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PATIENT INFORMATION

Patients should be advised to take Lopressor HCT (metoprolol tartrate and hydochlorothiazide) regularly and continuously, as directed, with or immediately following meals. If a dose should be missed, the patient should take only the next scheduled dose (without doubling it). Patients should not discontinue Lopressor HCT (metoprolol tartrate and hydochlorothiazide) without consulting the physician.

Patients should be advised (1) to avoid operating automobiles and machinery or engaging in other tasks requiring alertness until the patient's response to therapy with Lopressor HCT (metoprolol tartrate and hydochlorothiazide) has been determined; (2) to contact the physician if any difficulty in breathing occurs; (3) to inform the physician or dentist before any type of surgery that he or she is taking Lopressor HCT (metoprolol tartrate and hydochlorothiazide) .

Last reviewed on RxList: 5/9/2011
This monograph has been modified to include the generic and brand name in many instances.