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In this Article

• What is hydrochlorothiazide and metoprolol (Lopressor HCT)?
• What are the possible side effects of hydrochlorothiazide and metoprolol (Lopressor HCT)?
• What is the most important information I should know about hydrochlorothiazide and metoprolol (Lopressor HCT)?
• What should I discuss with my doctor before taking hydrochlorothiazide and metoprolol (Lopressor HCT)?
• How should I take hydrochlorothiazide and metoprolol (Lopressor HCT)?
• What happens if I miss a dose (Lopressor HCT)?
• What happens if I overdose (Lopressor HCT)?
• What should I avoid while taking hydrochlorothiazide and metoprolol (Lopressor HCT)?
• What other drugs will affect hydrochlorothiazide and metoprolol (Lopressor HCT)?
• Where can I get more information?

What happens if I miss a dose (Lopressor HCT)?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Lopressor HCT)?

Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include fast or slow heart rate, feeling like you might pass out, trouble breathing, or increased urination.

What should I avoid while taking hydrochlorothiazide and metoprolol (Lopressor HCT)?

Avoid drinking alcohol, which can lower your blood pressure and may add to the side effects of hydrochlorothiazide and metoprolol.

Avoid using other medicines that make you light-headed (especially narcotic pain medication or barbiturates). They can add to the side effects of hydrochlorothiazide and metoprolol. Tell your doctor if you regularly use any of these medicines.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

What other drugs will affect hydrochlorothiazide and metoprolol (Lopressor HCT)?

Many drugs can interact with hydrochlorothiazide and metoprolol. Below is just a partial list. Tell your doctor if you are using:

• insulin or diabetes medicine you take by mouth;
• colestipol (Colestid) or cholestyramine (Prevalite, Questran);
• theophylline (Elixophyllin, Respbid, Slo-Bid, Theo-Dur, Uniphyl, and others);
• steroids (prednisone and others);
• HIV or AIDS medicine such as ritonavir (Norvir);
• an antidepressant such as bupropion (Wellbutrin, Zyban), fluoxetine (Prozac), or paroxetine (Paxil);
• an antibiotic such as rifampin (Rifadin, Rifamate, Rimactane) or terbinafine (Lamisil);
• anti-malaria medication such as hydroxychloroquine (Plaquenil);
• medicine to treat psychiatric or mood disorders, such as chlorpromazine (Thorazine), haloperidol (Haldol), lithium (Lithobid), or thioridazine (Mellaril);
• NSAIDs (non-steroidal anti-inflammatory drugs) such as aspirin, ibuprofen (Motrin, Advil), diclofenac (Voltaren), etodolac (Lodine), indomethacin, naproxen (Aleve, Naprosyn), and others; or
• other heart or blood pressure medications such as clonidine (Catapres), propafenone (Rythmol), quinidine (Quinidex, Quin-Release Quin-G) reserpine, or verapamil (Calan, Covera, Isoptin, Verelan).

This list is not complete and there may be other drugs that can interact with hydrochlorothiazide and metoprolol. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about hydrochlorothiazide and metoprolol.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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