"Scientists at the National Institutes of Health report they have discovered in mouse studies that a small molecule released in the spinal cord triggers a process that is later experienced in the brain as the sensation of itch.
LOPROX® Lotion (ciclopirox) 0.77% is for topical use.
Each gram of LOPROX® Lotion contains 7.70 mg of ciclopirox (as ciclopirox olamine) in a water miscible lotion base consisting of Purified Water USP, Cocamide DEA, Octyldodecanol NF, Mineral Oil USP, Stearyl Alcohol NF, Cetyl Alcohol NF, Polysorbate 60 NF, Myristyl Alcohol NF, Sorbitan Monostearate NF, Lactic Acid USP, and Benzyl Alcohol NF (1%) as preservative.
LOPROX® Lotion (ciclopirox lotion) contains a synthetic, broad-spectrum, antifungal agent ciclopirox (as ciclopirox olamine). The chemical name is 6-cyclohexyl-1 -hydroxy-4-methyl-2(1H)-pyridone, 2-aminoethanol salt.
The CAS Registry Number is 41621-49-2.
The chemical structure is:
LOPROX® Lotion (ciclopirox lotion) has a pH of 7.
What are the possible side effects of ciclopirox topical?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using ciclopirox and call your doctor at once if you have a serious side effect such as:
- unusual or severe itching, redness, burning, dryness, or irritation of treated skin; or
- discoloration or other changes in the nails.
Less serious side effects may include mild burning, itching, or redness.
This is not a complete list of side effects and others may occur. Call your doctor for...
What are the precautions when taking ciclopirox lotion (Loprox Lotion)?
Before using ciclopirox, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history.
Before having surgery, tell your doctors or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is unknown if this medication passes into breast milk. Consult your doctor before...
Last reviewed on RxList: 11/6/2008
This monograph has been modified to include the generic and brand name in many instances.
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