Lorabid (Loracarbef) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 8, 2012

Lorabid

Sinus Infection »

Sinus infection facts

Sinus infections are caused by infections from a pathogenic microorganism (virus, bacterium, or fungus), which grows within a sinus and causes intermittent blockage of the sinus ostium.
Most people do not transmit sinus infections; most clinicians agree that except for rare instances, sinus infections are not contagious but arise from mainly viruses and bacteria that, by chance, contaminate a person who sinuses support their proliferation because of minor, and rarely, major abnormalities in the person's sinus tissue (for example, swelling, inflammation, abnormal mucus production, and rarely, facial or nasal trauma).
Sinusitis is inflammation of the air cavities within the passages of the nose. Sinusitis can be caused by infection, but also can be caused by allergies and chemical or particulate irritation of the sinuses.
Sinusitis may be classified in several ways such as acute sinus infec...

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Please Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

DRUG DESCRIPTION

Loracarbef is a synthetic b-lactam antibiotic of the carbacephem class for oral administration. Chemically, carbacephems differ from cephalosporin-class antibiotics in the dihydrothiazine ring where a methylene group has been substituted for a sulfur atom.

The chemical name for loracarbef is: (6R,7S)-7-[(R)-2-amino-2-phenylacetamido]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2- carboxylic acid, monohydrate.

It is a white to off-white solid with a molecular weight of 367.8. The empirical formula is C₁₆H₁₆ClN₃O₄·H₂O.

Lorabid (loracarbef) Pulvules and Lorabid (loracarbef) for Oral Suspension are intended for oral administration only.

Each Pulvule contains loracarbef equivalent to 200 mg (0.57 mmol) or 400 mg (1.14 mmol) anhydrous loracarbef activity. They also contain cornstarch, dimethicone, F Dy & C blue No. 2, gelatin, iron oxides, magnesium stearate, titanium dioxide, and other inactive ingredients.

After reconstitution, each 5 ml of Lorabid for Oral Suspension contains loracarbef equivalent to 100 mg (0.286 mmol) or 200 mg (0.57 mmol) anhydrous loracarbef activity. The suspensions also contain cellulose, F Dy & C red No. 40, flavors, methylparaben, propylparaben, simethicone emulsion, sodium carboxymethylcellulose, sucrose, and xanthan gum.

What are the possible side effects of loracarbef (Lorabid, Lorabid Pulvules)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

diarrhea that is watery or bloody;
seizure (convulsions);
fever, sore throat, and joint pain with a severe blistering, peeling, and red skin rash;
easy bruising or bleeding, unusual weakness; or
skin rash, bruising, severe tingling,...

Read All Potential Side Effects and See Pictures of Lorabid »