Lorabid (Loracarbef) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Lorabid

Ear Infection (Otitis Media) »

Ear infection or inflammation (otitis media) facts

Otitis media (ear infection or inflammation) is the most common diagnosis in sick children in the U.S.
Otitis media features fever, ear pain, and a feeling of fullness in the ear; as well as fussiness and feeding problems in young children.
Otitis media is usually an infection and/or inflammation of the middle ear.
Ear infection or inflammation causes fluid buildup in the middle ear.
A cold or other respiratory infection can lead to ear infections or inflammation.
Exposure to other children's colds as often occurs in daycare centers, raises the risk of contracting otitis media (ear infection or inflammation).
Bottlefeeding increases the risk of ear infection or inflammation in babies.
Middle ear pus causes pain and temporary hearing loss.
Rupture of the eardrum allows the pus to drain into the ear canal.
Otitis ...

Read the Ear Infection (Otitis Media) article »

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Please Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

DRUG DESCRIPTION

Loracarbef is a synthetic b-lactam antibiotic of the carbacephem class for oral administration. Chemically, carbacephems differ from cephalosporin-class antibiotics in the dihydrothiazine ring where a methylene group has been substituted for a sulfur atom.

The chemical name for loracarbef is: (6R,7S)-7-[(R)-2-amino-2-phenylacetamido]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2- carboxylic acid, monohydrate.

It is a white to off-white solid with a molecular weight of 367.8. The empirical formula is C₁₆H₁₆ClN₃O₄·H₂O.

Lorabid (loracarbef) Pulvules and Lorabid (loracarbef) for Oral Suspension are intended for oral administration only.

Each Pulvule contains loracarbef equivalent to 200 mg (0.57 mmol) or 400 mg (1.14 mmol) anhydrous loracarbef activity. They also contain cornstarch, dimethicone, F Dy & C blue No. 2, gelatin, iron oxides, magnesium stearate, titanium dioxide, and other inactive ingredients.

After reconstitution, each 5 ml of Lorabid for Oral Suspension contains loracarbef equivalent to 100 mg (0.286 mmol) or 200 mg (0.57 mmol) anhydrous loracarbef activity. The suspensions also contain cellulose, F Dy & C red No. 40, flavors, methylparaben, propylparaben, simethicone emulsion, sodium carboxymethylcellulose, sucrose, and xanthan gum.

What are the possible side effects of loracarbef (Lorabid, Lorabid Pulvules)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

diarrhea that is watery or bloody;
seizure (convulsions);
fever, sore throat, and joint pain with a severe blistering, peeling, and red skin rash;
easy bruising or bleeding, unusual weakness; or
skin rash, bruising, severe tingling,...

Read All Potential Side Effects and See Pictures of Lorabid »