July 30, 2016

Lorenzo's Oil

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How does Lorenzo's Oil work?

Adrenoleukodystrophy and adrenomyeloneuropathy are two rare genetic disorders that cause a large build-up of certain chemicals called very long-chain fatty acids. Lorenzo's oil might help prevent some of this build-up. The build-up of these fatty acids is thought to cause many serious problems throughout the brain and body.

Are there safety concerns?

Lorenzo's oil seems to be safe when used under the care of health professionals. Side effects of Lorenzo's oil can include bruising and bleeding.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of Lorenzo's oil during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Blood disorders that cause a decrease in blood platelets needed for clotting (thrombocytopenia) or a decrease in white cells needed to fight infections (neutropenia): Lorenzo's oil might make these conditions worse.

Dosing considerations for Lorenzo's Oil.

The following doses have been studied in scientific research:

BY MOUTH:
  • For adrenoleukodystrophy (ALD): a dose of Lorenzo's oil that provides about 20% of daily calories has been used. In another study, 300 mg/kg/day of erucic acid and 1.7 grams/kg/day of oleic acid (both contained in Lorenzo's oil) were used.

Therapeutic Research Faculty copyright

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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