"The the European Medicines Agency's (EMA's) Pharmacovigilance Risk Assessment Committee (PRAC) will review the risks and benefits of modified- and prolonged-release paracetamol (acetaminophen) tablets, the agency said today.
Lortab 2.5 Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Lortab 2.5 (hydrocodone bitartrate and acetaminophen) is a combination pain reliever containing an opiate (narcotic) pain reliever and a non-narcotic pain reliever used to relieve moderate to severe pain. Commonly side effects of Lortab 2.5 include drowsiness, nausea, vomiting, upset stomach, constipation, unclear thinking, anxiety, dizziness, headache, mood changes, blurred vision, ringing in your ears, or dry mouth. Lortab 2.5 (hydrocodone bitartrate and acetaminophen) is a combination pain reliever containing an opiate (narcotic) pain reliever, hydrocodone and the non-narcotic pain reliever acetaminophen. It is used to relieve moderate to severe pain. Among the most commonly reported side effects are drowsiness, nausea, vomiting, constipation, and unclear thinking.
The usual adult dosage of Lortab 2.5 is one or two tablets every four to six hours as needed for pain. Lortab 2.5 may interact with alcohol, other narcotic pain medications, sedatives, tranquilizers, sleeping pills, muscle relaxers, other medicines that can make you sleepy or slow your breathing, antidepressants, MAO inhibitors, atropine, benztropine, dimenhydrinate, glycopyrrolate, mepenzolate, methscopolamine, scopolamine, bladder or urinary medications, bronchodilators, or irritable bowel medications. Tell your doctor all medications and supplements you use. This medication should be used only when clearly needed during pregnancy. It is not recommended for use for long periods or in high doses near the expected delivery date because of the potential for harm to an unborn baby. Discuss the risks and benefits with your doctor. Based on information from related drugs, this drug may pass into breast milk. Due to the potential risk to the infant, consult your doctor before breastfeeding. Narcotic pain relievers have the potential to become habit-forming and to work less effectively when taken over long periods of time.
Our Lortab 2.5 (hydrocodone bitartrate and acetaminophen) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Lortab 2.5 in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
- shallow breathing, slow heartbeat;
- feeling light-headed, fainting;
- confusion, fear, unusual thoughts or behavior;
- seizure (convulsions);
- problems with urination; or
- nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
- anxiety, dizziness, drowsiness;
- mild nausea, vomiting, upset stomach, constipation;
- headache, mood changes;
- blurred vision;
- ringing in your ears; or
- dry mouth.
Read the entire detailed patient monograph for Lortab 2.5 (Hydrocodone Bitartrate and Acetaminophen Tablets)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Lortab 2.5 FDA Prescribing Information: Side Effects
The most frequently reported adverse reactions are lightheadedness, dizziness, sedation, nausea and vomiting. These effects seem to be more prominent in ambulatory than in non-ambulatory patients, and some of these adverse reactions may be alleviated if the patient lies down.
Other Adverse reactions include:
Gastrointestinal System: Prolonged administration of Lortab 2.5 (hydrocodone bitartrate and acetaminophen tablets) /500 tablets may produce constipation.
Special Senses: Cases of hearing impairment or permanent loss have been reported predominantly in patients with chronic overdose.
Potential effects of high dosage are listed in the OVERDOSAGE section.
DRUG ABUSE AND DEPENDENCE:
Controlled Substance: Lortab 2.5 (hydrocodone bitartrate and acetaminophen tablets) /500 tablets (Hydrocodone Bitartrate and Acetaminophen Tablets, USP, 2.5 mg/500 mg) are classified as a Schedule III controlled substance.
Abuse and Dependence: Psychic dependence, physical dependence, and tolerance may develop upon repeated administration of narcotics; therefore, this product should be prescribed and administered with caution. However, psychic dependence is unlikely to develop when hydrocodone bitartrate and acetaminophen tablets are used for a short time for the treatment of pain.
Physical dependence, the condition in which continued administration of the drug is required to prevent the appearance of a withdrawal syndrome, assumes clinically significant proportions only after several weeks of continued narcotic use, although some mild degree of physical dependence may develop after a few days of narcotic therapy. Tolerance, in which increasingly large doses are required in order to produce the same degree of analgesia, is manifested initially by a shortened duration of analgesic effect, and subsequently by decreases in the intensity of analgesia. The rate of development of tolerance varies among patients.
Read the entire FDA prescribing information for Lortab 2.5 (Hydrocodone Bitartrate and Acetaminophen Tablets)
Additional Lortab 2.5 Information
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