"A class of medications long used to curb HIV infection shows promise as a therapy for age-related macular degeneration (AMD), suggest findings from an NIH-funded study. These mainstay HIV drugs, called nucleoside reverse transcriptase inhibitors "...
(loteprednol etabonate) Ophthalmic Suspension 0.5%
STERILE OPHTHALMIC SUSPENSION
Loteprednol etabonate is represented by the following structural formula:
Chemical Name: chloromethyl 17α-[(ethoxycarbonyl)oxy]-11β-hydroxy-3-oxoandrosta-1,4-diene-17β-carboxylate
Each mL contains
ACTIVE: Loteprednol Etabonate 5 mg (0.5%);
INACTIVES: Edetate Disodium, Glycerin, Povidone, Purified Water and Tyloxapol.
Hydrochloric Acid and/or Sodium Hydroxide may be added to adjust the pH to 5.5-5.6.
The suspension is essentially isotonic with a tonicity of 250 to 310 mOsmol/kg.
PRESERVATIVE ADDED: Benzalkonium Chloride 0.01%.
What are the possible side effects of loteprednol ophthalmic (Alrex, Lotemax)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using loteprednol and call your doctor at once if you have:
- signs of a new eye infection such as swelling, redness, irritation, or drainage;
- blurred vision, eye pain, or seeing halos around lights;
- problems with your vision; or
- severe pain, burning or stinging when using the eye drops.
Common side effects may include:
- minor burning when using...
What are the precautions when taking loteprednol etabonate ophthalmic suspension (Lotemax)?
Before using loteprednol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: eye infections, cataracts, glaucoma (open-angle type), severe nearsightedness (myopia), diabetes.
After you apply this drug, your vision may become temporarily blurred. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs,...
Last reviewed on RxList: 5/6/2008
This monograph has been modified to include the generic and brand name in many instances.
Additional Lotemax Information
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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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