"A class of medications long used to curb HIV infection shows promise as a therapy for age-related macular degeneration (AMD), suggest findings from an NIH-funded study. These mainstay HIV drugs, called nucleoside reverse transcriptase inhibitors "...
(loteprednol etabonate) Ophthalmic Gel 0.5%
LOTEMAX (loteprednol etabonate ophthalmic gel) 0.5% contains a sterile, topical corticosteroid for ophthalmic use. Loteprednol etabonate is a white to off-white powder.
Loteprednol etabonate is represented by the following structural formula:
Chemical Name: chloromethyl 17α-[(ethoxycarbonyl)oxy]-11β-hydroxy-3-oxoandrosta-1,4-diene-17β-carboxylate
Each gram contains:
Active: Loteprednol Etabonate 5 mg (0.5%);
Inactives: Boric acid, edetate disodium dihydrate, glycerin, polycarbophil, propylene glycol, sodium chloride, tyloxapol, water for injection, and sodium hydroxide to adjust to a pH of between 6 and 7.
Preservative: benzalkonium chloride 0.003%.
What are the possible side effects of loteprednol ophthalmic (Alrex, Lotemax)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using loteprednol and call your doctor at once if you have:
- signs of a new eye infection such as swelling, redness, irritation, or drainage;
- blurred vision, eye pain, or seeing halos around lights;
- problems with your vision; or
- severe pain, burning or stinging when using the eye drops.
Common side effects may include:
- minor burning when using...
Last reviewed on RxList: 10/26/2012
This monograph has been modified to include the generic and brand name in many instances.
Additional Lotemax Gel Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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