"Dec. 18, 2012 -- People who can't get their high blood pressure down with drugs may be helped by a new procedure that deactivates overactive nerves in the kidneys, a small study shows.
The procedure is already available in Europe and "...
Lotrel Patient Information including How Should I Take
In this Article
- What is amlodipine and benazepril (Lotrel)?
- What are the possible side effects of amlodipine and benazepril (Lotrel)?
- What is the most important information I should know about amlodipine and benazepril (Lotrel)?
- What should I discuss with my healthcare provider before taking amlodipine and benazepril (Lotrel)?
- How should I take amlodipine and benazepril (Lotrel)?
- What happens if I miss a dose (Lotrel)?
- What happens if I overdose (Lotrel)?
- What should I avoid while taking amlodipine and benazepril (Lotrel)?
- What other drugs will affect amlodipine and benazepril (Lotrel)?
- Where can I get more information?
What should I discuss with my healthcare provider before taking amlodipine and benazepril (Lotrel)?
You should not use this medicine if:
- you are allergic to amlodipine (Norvasc, Caduet, Exforge, Lotrel, Tekamlo, Tribenzor, Twynsta, Amturnide) or benazepril (Lotensin);
- you have ever had angioedema (hives or severe swelling of deep skin tissues sometimes caused by allergic reaction); or
- you are allergic to any other ACE inhibitor, such as captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik).
If you have diabetes or kidney disease, you may not be able to take amlodipine and benazepril if you are also taking a blood pressure medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, or Valturna).
To make sure amlodipine and benazepril is safe for you, tell your doctor if you have:
- kidney disease (or if you are on dialysis);
- liver disease;
- heart disease or congestive heart failure;
- a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis;
- if you are on a low-salt diet.
FDA pregnancy category D. Do not use if you are pregnant. Stop using and tell your doctor right away if you become pregnant. Amlodipine and benazepril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control.
Amlodipine and benazepril can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using this medication.
How should I take amlodipine and benazepril (Lotrel)?
Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Your doctor may occasionally change your dose to make sure you get the best results.
Amlodipine and benazepril can be taken with or without food. Take the medicine at the same time each day.
Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medication, which can lead to severely low blood pressure or a serious electrolyte imbalance.
Your blood pressure will need to be checked often. You may also need frequent blood tests at your doctor's office.
If you need surgery, tell the surgeon ahead of time that you are using amlodipine and benazepril. You may need to stop using the medicine for a short time.
Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
Store at room temperature away from moisture and heat.
Additional Lotrel Information
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Report Problems to the Food and Drug Administration
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