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Lotrisone

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Since 2009, the Food and Drug Administratio"...

Lotrisone

INDICATIONS

LOTRISONE cream is a combination of an azole antifungal and corticosteroid and is indicated for the topical treatment of symptomatic inflammatory tinea pedis, tinea cruris, and tinea corporis due to Epidermophyton floccosum, Trichophyton mentagrophytes, and Trichophyton rubrum in patients 17 years and older.

DOSAGE AND ADMINISTRATION

Treatment of tinea corporis or tinea cruris:

  • Apply a thin film of LOTRISONE cream into the affected skin areas twice a day for one week.
  • Do not use more than 45 grams per week. Do not use with occlusive dressings.
  • If a patient shows no clinical improvement after 1 week of treatment with LOTRISONE cream, the diagnosis should be reviewed.
  • Do not use longer than 2 weeks.

Treatment of tinea pedis:

  • Gently massage a sufficient amount of LOTRISONE cream into the affected skin areas twice a day for two weeks.
  • Do not use more than 45 grams per week. Do not use with occlusive dressings.
  • If a patient shows no clinical improvement after 2 week of treatment with LOTRISONE cream, the diagnosis should be reviewed.
  • Do not use longer than 4 weeks. LOTRISONE cream is for topical use only. It is not for oral, ophthalmic, or intravaginal use.

HOW SUPPLIED

Dosage Forms And Strengths

Cream, 1%/0.05%. Each gram of LOTRISONE cream contains 10 mg of clotrimazole and 0.643 mg of betamethasone dipropionate (equivalent to 0.5 mg of betamethasone) in a white to off-white cream base.

Storage And Handling

LOTRISONE cream is white to off-white and supplied in 15-gram (NDC 0085-0924-01) and 45-gram tubes (NDC 0085-0924-02), boxes of one.

Store at 20°C-25°C (68°F-77°F); excursions permitted to 15°-30°C (59°-86°F) [see USP Controlled Room Temperature].

Manufactured by: Schering Plough Canada Inc., Pointe Claire, Quebec H9R 1B4. Revised: April 2014

Last reviewed on RxList: 5/1/2014
This monograph has been modified to include the generic and brand name in many instances.

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