(omega-3-acid ethyl esters) Capsules
LOVAZA, a lipid-regulating agent, is supplied as a liquid-filled gel capsule for oral administration. Each 1-gram capsule of LOVAZA contains at least 900 mg of the ethyl esters of omega-3 fatty acids sourced from fish oils. These are predominantly a combination of ethyl esters of eicosapentaenoic acid (EPA - approximately 465 mg) and docosahexaenoic acid (DHA - approximately 375 mg).
The empirical formula of EPA ethyl ester is C22H34O2, and the molecular weight of EPA ethyl ester is 330.51. The structural formula of EPA ethyl ester is:
The empirical formula of DHA ethyl ester is C24H36O2, and the molecular weight of DHA ethyl ester is 356.55. The structural formula of DHA ethyl ester is:
LOVAZA capsules also contain the following inactive ingredients: 4 mg a-tocopherol (in a carrier of soybean oil), and gelatin, glycerol, and purified water (components of the capsule shell).
What are the possible side effects of omega-3 polyunsaturated fatty acids?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have any of these serious side effects:
- fever, chills, body aches, flu symptoms;
- chest pain; or
- uneven heartbeats.
Less serious side effects may include:
- back pain;
- unusual or unpleasant taste in your mouth;
- upset stomach, belching; or
- mild skin rash.
What are the precautions when taking omega-3-acid ethyl esters (Lovaza)?
Before taking omega-3 acid ethyl esters, tell your doctor or pharmacist if you are allergic to it; or to fish, or shellfish, or soy products; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: alcohol use, diabetes, liver disease, underactive thyroid (hypothyroidism).
This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.
This medication passes into breast milk. Consult your doctor before...
Last reviewed on RxList: 6/2/2014
This monograph has been modified to include the generic and brand name in many instances.
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