"The U.S. Food and Drug Administration today approved the first generic version of Lovenox (enoxaparin sodium injection), an anti-coagulant drug used to prevent deep vein thrombosis (DVT), a potentially deadly blood clotting condition.
Lovenox Patient Information including How Should I Take
In this Article
- What is enoxaparin (Lovenox)?
- What are the possible side effects of enoxaparin (Lovenox)?
- What is the most important information I should know about enoxaparin (Lovenox)?
- What should I discuss with my healthcare provider before using enoxaparin (Lovenox)?
- How should I use enoxaparin (Lovenox)?
- What happens if I miss a dose (Lovenox)?
- What happens if I overdose (Lovenox)?
- What should I avoid while using enoxaparin (Lovenox)?
- What other drugs will affect enoxaparin (Lovenox)?
- Where can I get more information?
What should I discuss with my healthcare provider before using enoxaparin (Lovenox)?
You should not use this medication if you are allergic to enoxaparin, heparin, benzyl alcohol, or pork products, or if you have:
- active or uncontrolled bleeding; or
- a low level of platelets in your blood after testing positive for a certain antibody while using enoxaparin.
Enoxaparin may cause you to bleed more easily, especially if you have:
- a bleeding disorder that is inherited or caused by disease;
- hemorrhagic stroke;
- an infection of the lining of your heart (also called bacterial endocarditis);
- stomach or intestinal bleeding or ulcer; or
- recent brain, spine, or eye surgery.
Enoxaparin can cause a very serious blood clot around your brain or spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). This type of blood clot could cause long-term paralysis, and may be more likely to occur if you have:
- a genetic spinal defect;
- a history of spinal surgery or repeated spinal taps; or
- if you are using other medications to treat or prevent blood clots.
To make sure you can safely use enoxaparin, tell your doctor if you have other medical conditions, especially:
- kidney or liver disease;
- uncontrolled high blood pressure;
- eye problems caused by diabetes;
- recent stomach ulcer; or
- if you have ever had low blood platelets after receiving heparin.
FDA pregnancy category B. Enoxaparin is not expected to harm an unborn baby. However, some forms of this medication contain a preservative that may be harmful to a newborn. Tell your doctor if you are pregnant or plan to become pregnant during treatment. If you use this medication during pregnancy, make sure your doctor knows if you have a mechanical heart valve.
It is not known whether enoxaparin passes into breast milk or if it could harm a nursing baby. Do not receive this medication without telling your doctor if you are breast-feeding a baby.
How should I use enoxaparin (Lovenox)?
Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Enoxaparin is usually given every day until your bleeding condition improves. Follow the directions on your prescription label.
Enoxaparin is injected under the skin or into a vein through an IV. You may be shown how to use injections at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.
You should be sitting or lying down during the injection. Do not inject enoxaparin into a muscle.
Use a different place on your stomach each time you give an injection under the skin. Your care provider will show you the best places on your body to inject the medication. Do not inject into the same place two times in a row.
Prepare your dose in a syringe only when you are ready to give yourself an injection. Do not mix enoxaparin with other medications in the same IV. Do not use the medication if it has changed colors or has particles in it. Call your doctor for a new prescription.
Use a disposable needle only once. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.
Tell any doctor who treats you that you are using enoxaparin. If you need surgery or dental work, tell the surgeon or dentist ahead of time that you are using this medication.
To be sure this medication is not causing harmful effects, your blood and your stool (bowel movement) may need to be tested often. Your nerve and muscle function may also need to be tested. Visit your doctor regularly.
Store enoxaparin vials (bottles) at room temperature away from moisture and heat. Once you have used a vial for the first time, the medicine will keep at room temperature for up to 28 days. Throw away the vial after 28 days have passed since you first used the vial, even if there is still medicine left in it.
Additional Lovenox Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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