Loxapine (Loxapine Succinate) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 10, 2012

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Loxapine

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LOXAPINE
(loxapine (loxapine (loxapine (loxapine succinate) succinate) succinate) succinate) Capsule

DRUG DESCRIPTION

Loxapine (loxapine (loxapine (loxapine succinate) succinate) succinate) , a dibenzoxazepine compound, represents a subclass of tricyclic antipsychotic agents, chemically distinct from the thioxanthenes, butyrophenones, and phenothiazines. Chemically, it is 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepine. It is present as the succinate salt.

LOXAPINE (loxapine succinate) Structural Formula Illustration

LOXAPINE (loxapine (loxapine (loxapine succinate) succinate) succinate) BASE

Each capsule for oral administration, contains loxapine (loxapine (loxapine (loxapine succinate) succinate) succinate) succinate 6.8, 13.6, 34.0 or 68.1 mg equivalent to 5, 10, 25 or 50 mg of loxapine (loxapine (loxapine (loxapine succinate) succinate) succinate) base respectively. It also contains the following inactive ingredients: anhydrous lactose, benzyl alcohol NF, butyl paraben NF, edetate calcium disodium USP, gelatin, magnesium stearate, methyl paraben NF, polacrilin potassium, propyl paraben NF, sodium lauryl sulfate NF, sodium propionate NF, talc, and titanium dioxide. Additionally, the 10 mg capsule contains D&C Yellow 10 and FD&C Yellow 6, the 25 mg capsule contains D&C Yellow 10 and FD&C Blue 1, the 50 mg capsule contains FD&C Blue 1.

What are the precautions when taking loxapine succinate (Loxapine)?

See also Warning section.

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood problems (such as low red/white/platelet blood cell counts), a certain eye condition (glaucoma), heart problems (such as fast/irregular heartbeat, low blood pressure), liver disease, a brain disorder/tumor/injury, drug/alcohol/substance abuse, breast cancer, Parkinson's disease, seizures, a certain severe reaction to other antipsychotic-type medications (neuroleptic malignant...

Read All Potential Precautions of Loxapine »

Last reviewed on RxList: 8/19/2008
This monograph has been modified to include the generic and brand name in many instances.