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Lozol

What are diuretics and how do they work?

The amount of fluid (water) retained by the body is controlled primarily by the kidneys. This occurs due to the kidney's ability to control the retention and elimination of sodium and chloride, because the amounts of sodium, chloride, and water in the body are carefully balanced. Thus, if sodium and chloride are eliminated from the body, water also is eliminated. Conversely, if sodium and chloride are retained by the body, so is water.

The elimination of sodium, chloride, and water from the body is somewhat complex. In the kidneys, sodium, chloride, and other small molecules are filtered out of the blood and into the tubules of the kidney where urine is formed. Most of the sodium, chloride, and water are reabsorbed into the blood before the filtered fluid leaves the kidney in the form of urine. To make matters even more complex, there are different mechanisms that are active in different parts of the tu...

Lozol

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Lozol Drug Center

Medical Editor: John P. Cunha, DO, FACOEP

Lozol (indapamide) is used to treat fluid retention (edema) in people with congestive heart failure. This medication is also used to treat high blood pressure (hypertension). It is an oral antihypertensive/diuretic. Lozol is a discontinued brand name. This medication is available in generic form. Common side effects include dizziness or headache.

The adult starting dose of indapamide for hypertension is 1.25 mg as a single daily dose. Dose may be increased gradually to 5 mg if the response is not satisfactory. The adult starting dose for edema of congestive heart failure is 2.5 mg as a single daily dose taken in the morning. Dose may be increased to 5 mg if the response is not satisfactory. Indapamide may interact with lithium, baclofen, other blood pressure medications, steroids, oral insulin or diabetes medicine, aspirin and other salicylates, ACE inhibitors, NSAIDs (non-steroidal anti-inflammatory drugs), amiodarone, chloroquine, cisapride, clarithromycin, disopyramide, dofetilide, droperidol, erythromycin, haloperidol, pentamidine, pimozide, procainamide, quinidine, sotalol, or thioridazine. Tell your doctor all medications you are taking. During pregnancy, indapamide should be used only when prescribed. Diuretics (water pills) are not usually recommended to treat high blood pressure caused by pregnancy. It is unknown if this medication passes into breast milk or may harm a nursing infant. Consult your doctor before breast-feeding.

Our Lozol (indapamide) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Lozol Prescribing Information: Indications & Dosage

Lozol® (indapamide)  Structural Formula Illustration

Lozol (indapamide) is indicated for the treatment of hypertension, alone or in combination with other antihypertensive drugs.

Lozol (indapamide) is also indicated for the treatment of salt and fluid retention associated with congestive heart failure.

Usage in Pregnancy

The routine use of diuretics in an otherwise healthy woman is inappropriate and exposes mother and fetus to unnecessary hazard (see PRECAUTIONS below).

Diuretics do not prevent development of toxemia of pregnancy, and there is no satisfactory evidence that they are useful ...

Read the complete drug monograph for Lozol »

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Lozol Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have a serious side effect such as:

  • dry mouth, thirst, nausea, vomiting;
  • feeling weak, drowsy, restless, or light-headed;
  • fast or uneven heartbeat; or
  • muscle pain or weakness.

Less serious side effects may include:

  • dizziness;
  • headache; or
  • mild skin rash./...

Read the complete patient information for Lozol »

What is Consumer information?

A concise overview of the drug for the patient or caregiver from First DataBank.

Lozol Consumer Information: Uses

This medication is used to treat high blood pressure. Indapamide is also used to reduce extra salt and fluid in the body (edema) caused by a certain heart problem (congestive heart failure). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Decreasing extra salt and fluid in the body helps to decrease swelling and breathing problems from congestive heart failure and increases your ability to exercise.

Indapamide is a "water pill" (diuretic) that increases the amount of urine you make. Getting rid of extra water and salt may help to relax the blood vesse...

Read the complete consumer information for Lozol »

What is Lozol Consumer Information?

Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More

Lozol - User Reviews

Lozol User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Lozol sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Hypertension

Get tips on handling your hypertension.