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Lozol

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Lozol

Lozol®
(indapamide) 1.25 mg Tablets

Lozol

DRUG DESCRIPTION

Lozol® (indapamide) is an oral antihypertensive/diuretic. Its molecule contains both a polar sulfamoyl chlorobenzamide moiety and a lipid-soluble methylindoline moiety. It differs chemically from the thiazides in that it does not possess the thiazide ring system and contains only one sulfonamide group. The chemical name of Lozol (indapamide) is 1-(4-chloro-3sulfamoylbenzamido)-2-methylindoline, and its molecular weight is 365.84. The compound is a weak acid, pKa=8.8, and is soluble in aqueous solutions of strong bases. It is a white to yellow-white crystalline (tetragonal) powder.

Lozol® (indapamide)  Structural Formula Illustration

The tablets also contain microcrystalline cellulose, coloring agent, corn starch, pregelatinized starch, hypromellose, lactose, magnesium stearate, polyethylene glycol, and talc.

What are the possible side effects of indapamide (Lozol)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have a serious side effect such as:

  • dry mouth, thirst, nausea, vomiting;
  • feeling weak, drowsy, restless, or light-headed;
  • fast or uneven heartbeat; or
  • muscle pain or weakness.

Less serious side effects may include:

  • dizziness;
  • headache; or
  • mild skin rash.

This is not a complete...

Read All Potential Side Effects and See Pictures of Lozol »

What are the precautions when taking indapamide (Lozol)?

Before taking indapamide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, gout, kidney problems, liver disease, a certain nerve surgery (sympathectomy).

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

This medication may decrease your level of potassium in the blood. Before using potassium supplements or salt substitutes containing...

Read All Potential Precautions of Lozol »

Last reviewed on RxList: 10/16/2009
This monograph has been modified to include the generic and brand name in many instances.

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Lozol - User Reviews

Lozol User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Lozol sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Hypertension

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