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Planned initial single doses of ranibizumab injection 1 mg were associated with clinically significant intraocular inflammation in 2 of 2 neovascular AMD patients injected. With an escalating regimen of doses beginning with initial doses of ranibizumab injection 0.3 mg, doses as high as 2 mg were tolerated in 15 of 20 neovascular AMD patients.
LUCENTIS (ranibizumab injection) is contraindicated in patients with ocular or periocular infections.
LUCENTIS (ranibizumab injection) is contraindicated in patients with known hypersensitivity to ranibizumab or any of the excipients in LUCENTIS (ranibizumab injection) . Hypersensitivity reactions may manifest as severe intraocular inflammation.
Last reviewed on RxList: 7/21/2010
This monograph has been modified to include the generic and brand name in many instances.
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