"NEW YORK (Reuters Health) - New research in mice and human lung tissue suggests soluble ADAM33 (sADAM33) may prompt airway remodeling and boost allergic airway inflammation, making it a possible therapeutic target.
As Dr. Hans Michael"...
LUFYLLIN (dyphylline), a xanthine derivative, is a bronchodilator available for oral administration as tablets containing 200 mg and 400 mg of dyphylline. Other ingredients: magnesium stearate, microcrystalline cellulose.
Chemically, dyphylline is 7-(2,3-dihydroxypropyl)-theophylline, a white, extremely bitter, amorphous powder that is freely soluble in water and soluble in alcohol to the extent of 2 g/100 mL. Dyphylline forms a neutral solution that is stable in gastrointestinal fluids over a wide range of pH.
The molecular formula for dyphylline is C 10 H 14 N 4 O 4 with a molecular weight of 254.25. The structual formula is:
What are the possible side effects of dyphylline (Dilor, Dylix, Lufyllin, Neothylline)?
If you experience any of the following serious side effects, stop taking dyphylline and seek emergency medical attention:
- an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
- increased or irregular heartbeats; or
- severe nausea or vomiting.
Other, less serious side effects may occur although they are not common at appropriate doses. Continue to take dyphylline and talk to your doctor if you experience
- slight nausea, decreased...
What are the precautions when taking dyphylline (Lufyllin)?
Before using dyphylline, tell your doctor or pharmacist if you are allergic to it; or to theophylline, theobromine or caffeine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: glaucoma, diabetes, heart problems (e.g., angina, irregular heartbeat), high blood pressure, kidney disease, seizures, stomach/intestinal ulcer, overactive thyroid (hyperthyroidism).
This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic...
Last reviewed on RxList: 1/20/2005
This monograph has been modified to include the generic and brand name in many instances.
Additional Lufyllin Information
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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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