Lufyllin (Dyphylline) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 9, 2012

Lufyllin

Chronic Obstructive Pulmonary Disease »

What is COPD?

Chronic obstructive pulmonary disease (COPD) is comprised primarily of three related conditions - chronic bronchitis, chronic asthma, and emphysema. In each condition there is chronic obstruction of the flow of air through the airways and out of the lungs, and the obstruction generally is permanent and may be progressive over time.

While asthma features obstruction to the flow of air out of the lungs, usually, the obstruction is reversible. Between "attacks" of asthma the flow of air through the airways typically is normal. These patients do not have COPD. However, if asthma is left untreated, the chronic inflammation associated with this disease can cause the airway obstruction to become fixed. That is, between attacks, the asthmatic patient may then have abnormal air flow. This process is referred to as lung remodeling. These asthma patients with a fixed component of airway obstruction are also considered to have COPD.

Often patien...

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Lufyllin

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DRUG DESCRIPTION

LUFYLLIN (dyphylline), a xanthine derivative, is a bronchodilator available for oral administration as tablets containing 200 mg and 400 mg of dyphylline. Other ingredients: magnesium stearate, microcrystalline cellulose.

Chemically, dyphylline is 7-(2,3-dihydroxypropyl)-theophylline, a white, extremely bitter, amorphous powder that is freely soluble in water and soluble in alcohol to the extent of 2 g/100 mL. Dyphylline forms a neutral solution that is stable in gastrointestinal fluids over a wide range of pH.

The molecular formula for dyphylline is C ₁₀H ₁₄N ₄O ₄with a molecular weight of 254.25. The structual formula is:

What are the possible side effects of dyphylline (Dilor, Dylix, Lufyllin, Neothylline)?

If you experience any of the following serious side effects, stop taking dyphylline and seek emergency medical attention:

an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
seizures;
increased or irregular heartbeats; or
severe nausea or vomiting.

Other, less serious side effects may occur although they are not common at appropriate doses. Continue to take dyphylline and talk to your doctor...

Read All Potential Side Effects and See Pictures of Lufyllin »

What are the precautions when taking dyphylline (Lufyllin)?

Before using dyphylline, tell your doctor or pharmacist if you are allergic to it; or to theophylline, theobromine or caffeine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: glaucoma, diabetes, heart problems (e.g., angina, irregular heartbeat), high blood pressure, kidney disease, seizures, stomach/intestinal ulcer, overactive thyroid (hyperthyroidism).

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic...

Read All Potential Precautions of Lufyllin »

Last reviewed on RxList: 1/20/2005
This monograph has been modified to include the generic and brand name in many instances.