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Lufyllin Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Lufyllin (dyphylline) is a bronchodilator used to treat the symptoms of asthma, bronchitis, and emphysema. Common side effects include stomach pain/cramping, nausea, vomiting, diarrhea, loss of appetite, headache, trouble sleeping, irritability, restlessness, nervousness, shaking, flushing, and increased urination.
The usual adult dosage of Lufyllin is up to 15 mg/kg every six hours. Lufyllin may interact with alcohol, cimetidine, antibiotics, disulfiram, estrogens, fluvoxamine, methotrexate, mexiletine and propafenone, propranolol, tacrine, ticlopidine, verapamil, aminoglutethimide, carbamazepine, isoproterenol, moricizine, phenobarbital, phenytoin, rifampin, and sucralfate. Tell your doctor all medications and supplements you use. During pregnancy, Lufyllin should be used only if prescribed. This drug passes into breast milk and may have undesirable effects on a nursing infant (e.g., irritability). Consult your doctor before breastfeeding.
Our Lufyllin (dyphylline) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Lufyllin in Detail - Patient Information: Side Effects
If you experience any of the following serious side effects, stop taking dyphylline and seek emergency medical attention:
- an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
- increased or irregular heartbeats; or
- severe nausea or vomiting.
Other, less serious side effects may occur although they are not common at appropriate doses. Continue to take dyphylline and talk to your doctor if you experience
- slight nausea, decreased appetite, or weight loss;
- restlessness, tremor, or insomnia; or
- headache, lightheadedness, or dizziness.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Lufyllin (Dyphylline)
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Lufyllin Overview - Patient Information: Side Effects
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious side effects occur: confusion, dizziness, mental/mood changes, muscle twitching/pain/tenderness, weakness, rapid breathing.
Tell your doctor immediately if any of these rare but very serious side effects occur: fainting, fast/slow/irregular heartbeat, vomit that looks like coffee grounds, dark/tarry stools, blood in urine, seizures.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, red/scaly skin, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Lufyllin (Dyphylline)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Lufyllin FDA Prescribing Information: Side Effects
Adverse reactions with the use of LUFYLLIN (dyphylline) have been infrequent, relatively mild, and rarely required reduction in dosage or withdrawal of therapy.
The following adverse reactions which have been reported with other xanthine bronchodilators, and which have most often been related to excessive drug plasma levels, should be considered as potential adverse effects when dyphylline is administered:
Read the entire FDA prescribing information for Lufyllin (Dyphylline)
Additional Lufyllin Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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