Recommended Topic Related To:

Lunesta

"Sleep disorder drugs (hypnotic and sedative drugs) overview

Insomnia, a disorder in which there is difficulty sleeping, occurs occasionally in most people but usually lasts only a few days. The body then "corrects" itself "...

Lunesta

LUNESTA®
(eszopiclone) Film-coated Tablets for Oral Administration

Lunesta

DRUG DESCRIPTION

LUNESTA (eszopiclone) is a nonbenzodiazepine hypnotic agent that is a pyrrolopyrazine derivative of the cyclopyrrolone class. The chemical name of eszopiclone is (+)-(5S)-6-(5chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b] pyrazin-5-yl 4-methylpiperazine-1carboxylate. Its molecular weight is 388.81, and its empirical formula is C17H17ClN6O3. Eszopiclone has a single chiral center with an (S)-configuration. It has the following chemical structure:

LUNESTA® (eszopiclone) Structural Formula Illustration

Eszopiclone is a white to light-yellow crystalline solid. Eszopiclone is very slightly soluble in water, slightly soluble in ethanol, and soluble in phosphate buffer (pH 3.2).

Eszopiclone is formulated as film-coated tablets for oral administration. LUNESTA tablets contain 1 mg, 2 mg, or 3 mg eszopiclone and the following inactive ingredients: calcium phosphate, colloidal silicon dioxide, croscarmellose sodium, hypromellose, lactose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, titanium dioxide, and triacetin. In addition, both the 1 mg and 3 mg tablets contain FD&C Blue #2.

What are the possible side effects of eszopiclone (Lunesta)?

Stop using eszopiclone and call your doctor at once if you have any of these serious side effects:

  • aggression, agitation, changes in behavior;
  • thoughts of hurting yourself; or
  • hallucinations (hearing or seeing things).

Less serious side effects may include:

  • day-time drowsiness, dizziness, "hangover" feeling;
  • problems with memory or concentration;
  • anxiety, depression, nervous feeling;
  • headache;
  • nausea, stomach pain, loss of appetite, constipation;
  • dry mouth;
  • unusual or unpleasant taste in your...

Read All Potential Side Effects and See Pictures of Lunesta »

What are the precautions when taking eszopiclone (Lunesta)?

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: intoxication with medications that depress the nervous system or your breathing (CNS/respiratory depressants such as alcohol or tranquilizers/sedatives).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, lung diseases (e.g., chronic obstructive pulmonary disease, sleep apnea), mental/mood problems...

Read All Potential Precautions of Lunesta »

Last reviewed on RxList: 2/18/2014
This monograph has been modified to include the generic and brand name in many instances.

A A A

Lunesta - User Reviews

Lunesta User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Lunesta sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Women's Health

Find out what women really need.

Related Supplements
advertisement
advertisement
Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations