Lupron (Leuprolide Acetate Injection) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

Pill Identifier Search

February 9, 2012

Lupron

Endometriosis »

What is endometriosis?

Endometriosis is the abnormal growth of cells (endometrial cells) similar to those that form the inside of the uterus, but in a location outside of the uterus. Endometrial cells are cells that are shed each month during menstruation. The cells of endometriosis attach themselves to tissue outside the uterus and are called endometriosis implants. These implants are most commonly found on the ovaries, the Fallopian tubes, outer surfaces of the uterus or intestines, and on the surface lining of the pelvic cavity. They can also be found in the vagina, cervix, and bladder, although less commonly than other locations in the pelvis. Rarely, endometriosis implants can occur outside the pelvis, on the liver, in old surgery scars, and even in or around the lung or brain. Endometrial implants, while they can cause problems, are benign (not cancerous).

Who is affected by endometriosis?

Endometriosis affects w...

Read the Endometriosis article »

« Previous
1
2
3
4
5
6
7
8
9
10
11
12
13
next »

Lupron User Reviews >>

Lupron

Prostate Cancer Slideshow Pictures

Medical Illustrations of the Prostate Image Collection

Screening Tests Every Man Needs Slideshow Pictures

font size

Lupron
(leuprolide acetate) Injection

DRUG DESCRIPTION

Leuprolide acetate is a synthetic nonapeptide analog of naturally occurring gonadotropin releasing hormone (GnRH or LH-RH). The analog possesses greater potency than the natural hormone. The chemical name is 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-Nethyl-L-prolinamide acetate (salt) with the following structural formula:

Lupron (Leuprolide acetate) structural formula illustration

LUPRON (leuprolide acetate injection) INJECTION is a sterile, aqueous solution intended for subcutaneous injection. It is available in a 2.8 mL multiple-dose vial containing leuprolide acetate (5 mg/mL), sodium chloride, USP (6.3 mg/mL) for tonicity adjustment, benzyl alcohol, NF as a preservative (9 mg/mL), and water for injection, USP. The pH may have been adjusted with sodium hydroxide, NF and/or acetic acid, NF.

What are the possible side effects of leuprolide (Eligard, Lupron, Lupron Depot, Lupron Depot-Gyn, Lupron Depot-Ped)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

bone pain;
swelling, rapid weight gain;
pain, burning, stinging, bruising, or redness where the medication was injected;
feeling like you might pass out;
painful or difficult urination;

Read All Potential Side Effects and See Pictures of Lupron »

What are the precautions when taking leuprolide acetate injection (Lupron)?

Before using leuprolide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as the preservative benzyl alcohol), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, heart disease (such as heart attack), stroke, family history of sudden cardiac death.

In adults, leuprolide may weaken your bones and increase your risk for bone loss (osteoporosis) if used for a long time. Before using this medication, tell your doctor or pharmacist if you have osteoporosis or if you have any of the following risk factors for osteoporosis: long-term...

Read All Potential Precautions of Lupron »

Last reviewed on RxList: 3/3/2011
This monograph has been modified to include the generic and brand name in many instances.