April 26, 2017
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Lupron Pediatric

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Lupron Depot Pediatric


Prior to starting therapy with LUPRON DEPOT-PED, patients should be informed that:

  • All formulations are contraindicated in women who are or may become pregnant. If this drug is used during pregnancy, or if the patient becomes pregnant while taking the drug, the patient should be informed of the potential risk to the fetus.
  • Continuous therapy is important and that adherence to a monthly drug administration schedule must be accepted if therapy is to be successful. If the monthly injection schedule is not followed, pubertal development may begin again.
  • During the first weeks of treatment, signs of puberty, e.g., vaginal bleeding, may occur. This is a common initial effect of the drug. If these symptoms continue beyond the second month of treatment, the physician should be notified.
  • The most common side effects related to treatment with 1-month or 3-month LUPRON DEPOT-PED in clinical studies are: pain, acne/seborrhea, injection site reactions including pain, swelling and abscess, rash including erythema multiforme, vaginitis/bleeding/discharge, increased weight, headache, and altered mood.
  • After injection, some pain and irritation is expected; however if more severe symptoms occur, the physician should be contacted. Any unusual signs or symptoms should be reported to the physician.

Last reviewed on RxList: 1/13/2017
This monograph has been modified to include the generic and brand name in many instances.

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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