"Young children have died or become seriously ill from accidental exposure to a skin patch containing fentanyl, a powerful pain reliever. As a result of this, the Food and Drug Administration (FDA) is issuing a Drug Safety Communication to warn pa"...
(fospropofol disodium) Injection, for Intravenous Use
LUSEDRA (fospropofol disodium injection) is an injection solution intended for intravenous administration as a sedative-hypnotic agent. LUSEDRA (fospropofol disodium injection) is an aqueous, sterile, nonpyrogenic, clear, colorless, iso-osmotic solution containing 35 mg/mL of fospropofol disodium. Fospropofol disodium is a water-soluble prodrug of propofol, chemically described as 2,6-diisopropylphenoxymethyl phosphate, disodium salt. The structural and molecular formulas are shown in Figure 1.
Molecular Formula: C13H19O5PNa2
Molecular Weight: 332.24
Figure 1. Structural and Molecular Formulas of Fospropofol Disodium
The inactive components include monothioglycerol (0.25 wt%) and tromethamine (0.12 wt%). LUSEDRA (fospropofol disodium injection) has a pH of 8.2 to 9.0. LUSEDRA (fospropofol disodium injection) does not contain any antimicrobial preservatives and is intended for single-use administration.
Last reviewed on RxList: 2/10/2010
This monograph has been modified to include the generic and brand name in many instances.
Additional Lusedra Information
- Lusedra Drug Interactions Center: fospropofol iv
- Lusedra Side Effects Center
- Lusedra FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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