"Healthcare providers and parents should stop giving codeine to children, according to a new clinical report from the American Academy of Pediatrics, published online September 19 in Pediatrics. The authors also call for formal restriction "...
Overdosage with LUSEDRA (fospropofol disodium injection) can cause cardiorespiratory depression. If overdosage occurs, LUSEDRA (fospropofol disodium injection) administration should be discontinued immediately. Respiratory depression may require manual or mechanical ventilation. Cardiovascular depression may require elevation of lower extremities, intravascular volume replacement, and/or pharmacological management.
Formate and phosphate are metabolites of LUSEDRA (fospropofol disodium injection) and may contribute to signs of toxicity following overdosage. Signs of formate toxicity are similar to those of methanol toxicity and are associated with anion-gap metabolic acidosis. Intravenous exposure to a large amount of phosphate could potentially cause hypocalcemia with paresthesia, muscle spasms, and seizures.
None.This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 12/29/2016
Additional Lusedra Information
- Lusedra Drug Interactions Center: fospropofol iv
- Lusedra Side Effects Center
- Lusedra FDA Approved Prescribing Information including Dosage
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