August 29, 2016
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"NEW YORK (Reuters Health) - Ovarian tissue cryopreservation and subsequent transplantation appears to be an effective alternative for fertility preservation in women being treated for cancer, according to data from the FertiPROTEKT network.





Serious ill effects have not been reported following acute ingestion of large doses of oral contraceptives by young children. Overdosage may cause nausea, and withdrawal bleeding may occur in females.

Noncontraceptive Health Benefits

The following noncontraceptive health benefits related to the use of oral contraceptives are supported by epidemiological studies which largely utilized oral-contraceptive formulations containing doses exceeding 0.035 mg of ethinyl estradiol or 0.05 mg of mestranol.

Effects on menses

· Increased menstrual cycle regularity

· Decreased blood loss and decreased incidence of iron-deficiency anemia

· Decreased incidence of dysmenorrhea

Effects related to inhibition of ovulation:

· Decreased incidence of functional ovarian cysts

· Decreased incidence of ectopic pregnancies

Effects from long-term use:

· Decreased incidence of fibroadenomas and fibrocystic disease of the breast

· Decreased incidence of acute pelvic inflammatory disease

· Decreased incidence of endometrial cancer

· Decreased incidence of ovarian cancer


Oral contraceptives should not be used in women with any of the following conditions:

· Thrombophlebitis or thromboembolic disorders

· A past history of deep-vein thrombophlebitis or thromboembolic disorders

· Cerebrovascular or coronary artery disease

· Known or suspected carcinoma of the breast

· Carcinoma of the endometrium or other known or suspected estrogen-dependent neoplasia

· Undiagnosed abnormal genital bleeding

· Cholestatic jaundice of pregnancy or jaundice with prior pill use

· Hepatic adenomas or carcinomas

· Known or suspected pregnancy

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 5/16/2006


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