Luxiq (Betamethasone Valerate Foam) Drug Information: Side Effects and Drug Interactions

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May 27, 2012

Luxiq

Allergy Drugs: Prescription and OTC »

Allergy medications overview

The arsenal of allergy drugs includes dozens of medications that relieve allergy symptoms when confronted with a trigger known as an allergen. That trigger could be something from a plant, such as pollen, or something from an animal (pet dander, dust mites, cockroaches). Other allergy triggers include certain fragrances or chemical substances.

What causes a person's allergic reaction is highly individual. But the reactions are often universal: swelling and inflammation, especially around the eyes, nose, and throat, usually accompanied by itching.

Some allergy medications work against the effects of histamines, which are released during an allergic reaction. Other medications reduce swelling, affect the immune system, or affect release of other substances associated with allergic reactions.

Many allergy drugs are available without a prescription.

For what conditions are allergy medicatio...

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Luxiq

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SIDE EFFECTS

The most frequent adverse event was burning/itching/stinging at the application site; the incidence and severity of this event were as follows:

Incidence and severity of burning/itching/stinging
Product	Total incidence	Maximum severity
Product	Total incidence	Mild	Moderate	Severe
Luxiq Foam n=63	34 (54%)	28 (44%)	5 (8%)	1 (2%)
Betamethasone valerate lotion n=63	33 (52%)	26(41%)	6 (10%)	1 (2%)
Placebo Foam n=32	24 (75%)	13(41%)	7 (22%)	41 (2%)
Placebo Lotion n=30	20 ( 6 7%)	12(40%)	5 (17%)	31 (0%)

Other adverse events which were considered to be possibly, probably, or definitely related to Luxiq (betamethasone valerate foam) occurred in 1 patient each; these were paresthesia, pruritus, acne, alopecia, and conjunctivitis.

The following additional local adverse reactions have been reported with topical corticosteroids, and they may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximately decreasing order of occurrence: irritation; dryness; folliculitis; acneiform eruptions; hypopigmentation; perioral dermatitis; allergic contact dermatitis; secondary infection; skin atrophy; striae; and miliaria.

Systemic absorption of topical corticosteroids has produced reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing's syndrome, hyperglycemia, and glucosuria in some patients.