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Postmarketing Experience

Hypersensitivity Reactions: Case series report an overall incidence of hypersensitivity reactions in approximately 2% of patients. Life- threatening anaphylactic reactions have occurred. Manifestations include respiratory distress, shock, angioedema, urticaria, pruritus. A death has been reported following administration of a similar compound employed to estimate the depth of a severe burn. Reactions are more likely to occur in patients with a personal or family history of bronchial asthma, significant allergies, drug reactions or previous reactions to triphenylmethane dyes [see WARNINGS and PRECAUTIONS].

Laboratory Tests: Lymphazurin (isosulfan blue) 1% interferes with measurements of oxygen saturation by pulse oximetry and of methemoglobin by gas analyzer [see WARNINGS and PRECAUTIONS].

Skin: transient or long-term (tattooing) blue coloration.

No drug interactions have been identified with Lymphazurin (isosulfan blue) 1%.

Last reviewed on RxList: 2/13/2008
This monograph has been modified to include the generic and brand name in many instances.