Lyrica (Pregabalin) Drug Information: Overdosage and Contraindications

Pill Identifier Search

May 27, 2012

Lyrica

Facial Nerve Problems and Bell's Palsy »

What is the facial nerve?

The facial nerve is a nerve which controls the muscles on the side of the face. It allows us to show expression, smile, cry, and wink. Injury to the facial nerve causes a socially and psychologically devastating physical defect; treatment may require extensive rehabilitation or multiple procedures.

The facial nerve is the seventh of the twelve cranial nerves. Everyone has two facial nerves, one for each side of the face. The facial nerve travels with the hearing nerve (the eighth cranial nerve) as it travels in and around the structures of the middle ear. It exits the front of the ear at the stylomastoid foramen (a hole in the skull base), where it then travels through the parotid gland. In the parotid gland it divides into many branches which provide motor function for the various muscles and glands of the head and neck.

What are symptoms of a facial nerve problem?

Facial nerve problems...

Read the Facial Nerve Problems and Bell's Palsy article »

« Previous
1
2
3
4
5
6
7
8
9
10
11
12
13
Next »

Lyrica User Reviews >>

Lyrica

Fibromyalgia Overview Slideshow

Take the Fibromyalgia Quiz

Coping With Fibromyalgia Slideshow Pictures

font size

OVERDOSE

Signs, Symptoms and Laboratory Findings of Acute Overdosage in Humans

There is limited experience with overdose of LYRICA. The highest reported accidental overdose of LYRICA during the clinical development program was 8000 mg, and there were no notable clinical consequences.

Treatment or Management of Overdose

There is no specific antidote for overdose with LYRICA. If indicated, elimination of unabsorbed drug may be attempted by emesis or gastric lavage; observe usual precautions to maintain the airway. General supportive care of the patient is indicated including monitoring of vital signs and observation of the clinical status of the patient. Contact a Certified Poison Control Center for upto-date information on the management of overdose with LYRICA.

Although hemodialysis has not been performed in the few known cases of overdose, it may be indicated by the patient's clinical state or in patients with significant renal impairment. Standard hemodialysis procedures result in significant clearance of pregabalin (approximately 50% in 4 hours).

CONTRAINDICATIONS

LYRICA is contraindicated in patients with known hypersensitivity to pregabalin or any of its components. Angioedema and hypersensitivity reactions have occurred in patients receiving pregabalin therapy.

Last reviewed on RxList: 6/10/2011
This monograph has been modified to include the generic and brand name in many instances.