November 25, 2015


font size

Are there any interactions with medications?

Calcium supplements
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Lysine can increase how much calcium the body absorbs. Taking calcium along with lysine can increase the amount of calcium in the body. Avoid taking large amounts of calcium and lysine at the same time.

Gastrointestinal agents (5-HT4 agonist)
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

Lysine might inhibit the effects of some gastrointestinal agents including prucalopride and tegaserod.

Dosing considerations for Lysine.

The following doses have been studied in scientific research:

  • For cold sores (herpes simplex labialis): 1000 mg daily for 12 months and 1000 mg three times daily for 6 months.
  • For treating cold sores (herpes simplex labialis): a specific combination of lysine plus zinc oxide and 14 other ingredients (Super Lysine Plus +) applied every 2 hours for 11 days has been used.

Therapeutic Research Faculty copyright

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Women's Health

Find out what women really need.

Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations