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DOSAGE AND ADMINISTRATION
The recommended initial dose of LYSODREN is 2 g to 6 g orally, in three or four divided doses per day. Increase doses incrementally to achieve a blood concentration of 14 to 20 mg/L, or as tolerated.
LYSODREN is a cytotoxic drug. Follow applicable special handling and disposal procedures.
Adrenal Crisis In The Setting Of Shock Or Severe Trauma
Discontinue LYSODREN until recovery [see WARNINGS AND PRECAUTIONS].
Central Nervous System (CNS) Toxicity
Discontinue LYSODREN until symptoms resolve. Seven to 10 days after symptoms resolve, restart at a lower dose (for example, decrease by 500-1000 mg) [see WARNINGS AND PRECAUTIONS].
Dosage Forms And Strengths
500 mg white, round, biconvex, scored tablets, bisected on one side and impressed with “BL” over “L1” on the other side.
Storage And Handling
LYSODREN tablets are supplied as 500 mg white, round, biconvex, scored tablets, bisected on one side and impressed with “BL” over “L1” on the other side.
100 tablets per bottle: NDC 0015-3080-60
Store bottles at 25°C (77°F); excursions permitted between 15°C and 30°C (59°F-86°F).
Mitotane is a cytotoxic drug. Follow applicable special handling and disposal procedures [see REFERENCES].
1. OSHA. http://www.osha.gov/SLTC/hazardousdrugs/index.html
Manufactured for: Bristol-Myers Squibb Company Princeton, New Jersey 08543 USA. Revised: March 2016This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 3/28/2016
Additional Lysodren Information
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