"Cancer patients with limited finances are more likely to have increased symptoms and poorer quality of life, say the authors of a new study published online February 29 in the Journal of Clinical Oncology.
The following adverse reactions are discussed in greater detail in other sections of the label:
- Adrenal Crisis in the Setting of Shock or Severe Trauma [see WARNINGS AND PRECAUTIONS]
- CNS Toxicity [see WARNINGS AND PRECAUTIONS]
- Adrenal Insufficiency [see WARNINGS AND PRECAUTIONS]
The following adverse reactions associated with the use of LYSODREN were identified in clinical trials or postmarketing reports. Because these reactions were reported voluntarily from a population of uncertain size, it is not always possible to estimate their frequency reliably or to establish a causal relationship to drug exposure.
Common adverse reactions occurring with LYSODREN treatment include:
- Anorexia, nausea, vomiting, and diarrhea (80%)
- Depression, dizziness, or vertigo (15%-40%)
- Rash (15%)
- Growth retardation, hypothyroidism
- Confusion, headache, ataxia, mental impairment, weakness, dysarthria
- Hepatitis, elevation of liver enzymes
- Hypercholesterolemia, hypertriglyceridemia
Less common adverse reactions include: visual blurring, diplopia, lens opacity, retinopathy, prolonged bleeding time, hematuria, hemorrhagic cystitis, albuminuria, hypertension, orthostatic hypotension, flushing, generalized aching, and fever.
Read the Lysodren (mitotane) Side Effects Center for a complete guide to possible side effects
Mitotane is a strong inducer of cytochrome P450 3A4 (CYP3A4). Monitor patients for a change in dosage requirements for the concomitant drug when administering LYSODREN to patients receiving drugs that are substrates of CYP3A4.
Read the Lysodren Drug Interactions Center for a complete guide to possible interactions
Last reviewed on RxList: 3/28/2016
Additional Lysodren Information
Lysodren - User Reviews
Lysodren User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Get the latest treatment options.