"A class of medications long used to curb HIV infection shows promise as a therapy for age-related macular degeneration (AMD), suggest findings from an NIH-funded study. These mainstay HIV drugs, called nucleoside reverse transcriptase inhibitors "...
Macugen Patient Information Including Side Effects
Brand Names: Macugen
Generic Name: pegaptanib ophthalmic injection (Pronunciation: peg AP ta nib off THAL mik in JEK tion)
- What is pegaptanib ophthalmic (Macugen)?
- What are the possible side effects of pegaptanib ophthalmic (Macugen)?
- What is the most important information I should know about pegaptanib ophthalmic (Macugen)?
- What should I discuss with my healthcare provider before taking pegaptanib ophthalmic (Macugen)?
- How should I take pegaptanib ophthalmic (Macugen)?
- What happens if I miss a dose (Macugen)?
- What happens if I overdose (Macugen)?
- What should I avoid while taking pegaptanib ophthalmic (Macugen)?
- What other drugs will affect pegaptanib ophthalmic (Macugen)?
- Where can I get more information?
What is pegaptanib ophthalmic (Macugen)?
Pegaptanib is made from a human antibody fragment. It works by keeping new blood vessels from forming under the retina (a sensory membrane that lines the inside of the eye). In people with a certain type of eye disease, new blood vessels grow under the retina where they leak blood and fluid. This is known as the "wet form" of macular degeneration.
Pegaptanib ophthalmic (for the eyes) is used to treat wet age-related macular degeneration.
Pegaptanib ophthalmic may also be used for purposes not listed in this medication guide.
What are the possible side effects of pegaptanib ophthalmic (Macugen)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- eye pain or redness, swelling around your eyes;
- sudden vision problems;
- seeing flashes of light or "floaters" in your vision;
- eyes being more sensitive to light;
- sudden numbness or weakness, especially on one side of the body; or
- sudden severe headache, confusion, problems with speech or balance.
Less serious side effects may include:
- watery eyes;
- blurred vision;
- swelling of the eyelids; or
- mild eye pain or discomfort after the injection.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the Macugen (pegaptanib sodium) Side Effects Center for a complete guide to possible side effects
What is the most important information I should know about pegaptanib ophthalmic (Macugen)?
You should not receive pegaptanib if you are allergic to it, or if you have cataracts or glaucoma, or any type of bacterial, fungal, or viral infection in or around your eyes.
Call your doctor at once if you have eye pain or redness, swelling or puffiness around your eyes, or sudden vision problems at any time during treatment.
Additional Macugen Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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