"Taking a widely used antidepressant during the first trimester of pregnancy is associated with an increased risk for congenital and cardiac malformations, concludes a systematic review and meta-analysis by Canadian researchers.
Makena Patient Information including How Should I Take
In this Article
- What is hydroxyprogesterone (Makena)?
- What are the possible side effects of hydroxyprogesterone (Makena)?
- What is the most important information I should know about hydroxyprogesterone (Makena)?
- What should I discuss with my healthcare provider before receiving hydroxyprogesterone (Makena)?
- How is hydroxyprogesterone given (Makena)?
- What happens if I miss a dose (Makena)?
- What happens if I overdose (Makena)?
- What should I avoid while receiving hydroxyprogesterone (Makena)?
- What other drugs will affect hydroxyprogesterone (Makena)?
- Where can I get more information?
What should I discuss with my healthcare provider before receiving hydroxyprogesterone (Makena)?
You should not receive this medication if you are allergic to hydroxyprogesterone or castor oil, or if you have:
- unusual vaginal bleeding that has not been checked by a doctor;
- liver disease or liver cancer;
- a hormone related cancer such as breast or uterine cancer;
- severe or uncontrolled high blood pressure;
- a history of jaundice caused by pregnancy; or
- a history of a stroke, blood clot, or circulation problems.
To make sure you can safely use hydroxyprogesterone, tell your doctor if you have any of these other conditions:
- eclampsia or preeclampsia of pregnancy;
- kidney disease;
- high blood pressure, heart disease;
- migraine headaches;
- a personal or family history of diabetes;
- depression; or
- fluid retention.
Hydroxyprogesterone passes into breast milk, but it is not known whether this could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How is hydroxyprogesterone given (Makena)?
Hydroxyprogesterone is injected into a muscle. You will receive this injection in a clinic or doctor's office.
Hydroxyprogesterone is usually started during the 16th week of pregnancy and given once per week until the 37th week or until your baby is born. Follow your doctor's instructions.
Your doctor will need to check your progress on a regular basis while you are using this medication. Do not miss any scheduled appointments. Every woman should remain under the care of a doctor during pregnancy.
Additional Makena Information
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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