- What other names is Manganese known by?
- What is Manganese?
- How does Manganese work?
- Are there safety concerns?
- Are there any interactions with medications?
- Dosing considerations for Manganese.
Manganese is used for prevention and treatment of manganese deficiency, a condition in which the body doesn't have enough manganese. It is also used for weak bones (osteoporosis), a type of "tired blood" (anemia), and symptoms of premenstrual syndrome (PMS).
Manganese is sometimes included with chondroitin sulfate and glucosamine hydrochloride in multi-ingredient products promoted for osteoarthritis.
Look out for manganese that is "hidden" in some supplements. Certain supplements, including those commonly used for osteoarthritis (e.g., CosaminDS), contain manganese. When using these products, it's important to follow label directions carefully. At doses slightly higher than the recommended dose, these products provide more than the Tolerable Upper Limit (UL) for adults, 11 mg of manganese per day. Consuming more than 11 mg per day of manganese could cause serious and harmful side effects.
- Low manganese levels in the body (manganese deficiency). Taking manganese by mouth or giving manganese intravenously (by IV) helps to treat or prevent low manganese levels in the body. Also, taking manganese by mouth along with other vitamins and minerals can promote growth in children who have low levels of manganese.
Possibly Effective for...
- Weak bones (osteoporosis). Taking manganese by mouth in combination with calcium, zinc, and copper seems to help reduce spinal bone loss in older women. Also, taking a specific product (Vitrum osteomag) containing manganese, calcium, vitamin D, magnesium, zinc, copper, and boron for one year seems to improve bone mass in women with weak bones.
Insufficient Evidence to Rate Effectiveness for...
- Complications of lung disease (chronic obstructive pulmonary disease, COPD). Early research suggests that giving manganese, selenium, and zinc intravenously (by IV) may help people with worsened COPD to breathe on their own without help from a machine sooner.
- Osteoarthritis. Taking a specific product (Cosamin DS from Nutramax Laboratories) containing manganese, glucosamine hydrochloride, and chondroitin sulfate by mouth for 4 months improves pain and the ability to do normal activities in people with osteoarthritis of the knee and the lower back. However, many studies show that taking glucosamine plus chondroitin without manganese can help treat osteoarthritis. Therefore, the effects of manganese are unclear.
- Premenstrual syndrome (PMS). Early research suggests that taking manganese along with calcium helps improve symptoms of PMS, including pain, crying, loneliness, anxiety, restlessness, irritability, mood swings, depression, and tension. Researchers aren't sure whether the improvement is due to the calcium or the manganese.
- Weight loss. Early research suggests that taking a specific product (7-Keto Naturalean) containing manganese, 7-oxo-DHEA, L-tyrosine, asparagus root extract, choline bitartrate, inositol, copper gluconate, and potassium iodide by mouth for 8 weeks can slightly reduce weight in overweight people.
- Wound healing. Early research suggests that applying a dressing containing manganese, calcium, and zinc to chronic wounds for 12 weeks may improve wound healing.
- Other conditions.
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).
Next: How does Manganese work?
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