"Nov. 2, 2012 -- Safety steps taken in the wake of the fungal meningitis outbreak have worsened drug shortages, raising questions about whether the U.S. must choose between the safety and the availability of crucial medicines.
- Clinician Information:
Marcaine Patient Information including If I Miss a Dose
In this Article
- What is bupivacaine (Marcaine)?
- What are the possible side effects of bupivacaine (Marcaine)?
- What is the most important information I should know about bupivacaine (Marcaine)?
- What should I discuss with my health care provider before receiving bupivacaine (Marcaine)?
- How is bupivacaine given (Marcaine)?
- What happens if I miss a dose (Marcaine)?
- What happens if I overdose (Marcaine)?
- What should I avoid after receiving bupivacaine (Marcaine)?
- What other drugs will affect bupivacaine (Marcaine)?
- Where can I get more information?
What happens if I miss a dose (Marcaine)?
Since bupivacaine is given as needed before a surgery or other medical procedure, you are not likely to be on a dosing schedule.
What happens if I overdose (Marcaine)?
Tell your caregivers right away if you think you have received too much of this medicine.
Overdose symptoms may include extreme drowsiness, fainting, seizure (convulsions), shallow breathing, or breathing that stops.
What should I avoid after receiving bupivacaine (Marcaine)?
This medication can cause numbness over a large portion of your body. Take care to avoid injury before the feeling has returned completely.
What other drugs will affect bupivacaine (Marcaine)?
Before receiving bupivacaine, tell your doctor if you are using any of the following drugs:
- a blood thinner such as warfarin (Coumadin);
- ergot medicine such as ergotamine (Ergomar, Cafergot), dihydroergotamine (D.H.E. 45, Migranal), ergonovine (Ergotrate), or methylergonovine (Methergine);
- an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate); or
- antidepressants such as amitriptyline (Elavil, Etrafon), amoxapine (Ascendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), or trimipramine (Surmontil).
If you are using any of these drugs, you may not be able to receive bupivacaine, or you may need dose adjustments or extra monitoring during anesthesia.
This list is not complete and there may be other drugs that can interact with bupivacaine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Where can I get more information?
Your doctor or pharmacist can provide more information about bupivacaine.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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Additional Marcaine Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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