July 25, 2016
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Marqibo

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Marqibo

Overdosage
Contraindications

OVERDOSE

When Marqibo (vinCRIStine sulfate LIPOSOME injection) was administered at a dose of 2.4 mg/m², severe toxicities including motor neuropathy of Grade 3, grand mal seizure of Grade 4, and elevated aspartate aminotransferase and hyperbilirubinemia of Grade 4 were reported in 1 patient each. There is no known antidote for overdosage.

CONTRAINDICATIONS

Marqibo is contraindicated in patients with demyelinating conditions including Charcot-Marie-Tooth syndrome.

Marqibo is contraindicated in patients with hypersensitivity to vincristine sulfate or any of the other components of Marqibo (vinCRIStine sulfate LIPOSOME injection).

Marqibo is contraindicated for intrathecal administration.

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 6/17/2016

Overdosage
Contraindications

Report Problems to the Food and Drug Administration

 

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