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Patients should be warned not to drink alcoholic beverages while on Matulane (procarbazine) therapy since there may be an Antabuse (disulfiram)-like reaction. They should also be cautioned to avoid foods with known high tyramine content such as wine, yogurt, ripe cheese and bananas. Over-the-counter drug preparations which contain antihistamines or sympathomimetic drugs should also be avoided. Patients taking Matulane (procarbazine) should also be warned against the use of prescription drugs without the knowledge and consent of their physician. Patients should be advised to discontinue tobacco use.

Last reviewed on RxList: 12/29/2008
This monograph has been modified to include the generic and brand name in many instances.