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Mavik

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Mavik

MAVIK®
(trandolapril) Tablets

Mavik

WARNING

FETAL TOXICITY

When pregnancy is detected, discontinue MAVIK as soon as possible.

Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus (See WARNINGS: Fetal Toxicity).

DRUG DESCRIPTION

Trandolapril is the ethyl ester prodrug of a nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, trandolaprilat. Trandolapril is chemically described as (2S, 3aR, 7aS)-1-[(S)-N-[(S)-1-Carboxy-3phenylpropyl]alanyl] hexahydro-2-indolinecarboxylic acid, 1-ethyl ester. Its empirical formula is C24H34N2O5 and its structural formula is

MAVIK® (trandolapril) Structural Formula Illustration

M.W. = 430.54
Melting Point = 125°C

Trandolapril is a white or almost white powder that is soluble ( > 100 mg/mL) in chloroform, dichloromethane, and methanol. MAVIK tablets contain 1 mg, 2 mg, or 4 mg of trandolapril for oral administration. Each tablet also contains corn starch, croscarmellose sodium, hypromellose, iron oxide, lactose monohydrate, povidone, sodium stearyl fumarate.

What are the possible side effects of trandolapril (Mavik)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • urinating less than usual, or not at all;
  • swelling, weight gain, feeling short of breath;
  • feeling like you might pass out;
  • chest pain, trouble breathing;
  • pounding heartbeats or fluttering in your chest;
  • fever, chills, body aches, flu symptoms;
  • easy bruising, unusual bleeding...

Read All Potential Side Effects and See Pictures of Mavik »

What are the precautions when taking trandolapril (Mavik)?

Before taking trandolapril, tell your doctor or pharmacist if you are allergic to it; or to other ACE inhibitors (e.g., benazepril, captopril); or if you have any other allergies (including exposure to certain membranes used for blood filtering). This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: history of an allergic reaction which included swelling of the face/lips/tongue/throat (angioedema).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, high blood...

Read All Potential Precautions of Mavik »

Last reviewed on RxList: 10/26/2012
This monograph has been modified to include the generic and brand name in many instances.

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Mavik - User Reviews

Mavik User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Mavik sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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