Maxaquin (Lomefloxacin Hcl) Drug Overview and Uses for Patients and Caregivers at RxList

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May 27, 2012

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Maxaquin

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Please Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Maxaquin (lomefloxacin hcl) ^Ò
lomefloxacin hydrochloride tablets (lomefloxacin hcl)

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Maxaquin (lomefloxacin hcl) and other antibacterial drugs, Maxaquin (lomefloxacin hcl) should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

DRUG DESCRIPTION

Maxaquin (lomefloxacin HCl) is a synthetic broad-spectrum antimicrobial agent for oral administration. Lomefloxacin HCl, a difluoroquinolone, is the monohydrochloride salt of (±)-1-ethyl-6, 8-difluoro-1, 4-dihydro-7- (3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid. Its empirical formula is C₁₇H₁₉F₂N₃O₃· HCl, and its structural formula is:

Lomefloxacin HCl is a white to pale yellow powder with a molecular weight of 387.8. It is slightly soluble in water and practically insoluble in alcohol. Lomefloxacin HCl is stable to heat and moisture but is sensitive to light in dilute aqueous solution.

Maxaquin (lomefloxacin hcl) is available as a film-coated tablet formulation containing 400 mg of lomefloxacin base, present as the hydrochloride salt. The base content of the hydrochloride salt is 90.6%. The inactive ingredients are carboxymethylcellulose calcium, hydroxypropyl cellulose, hypromellose, lactose, magnesium stearate, polyethylene glycol, polyoxyl 40 stearate, and titanium dioxide.

Last reviewed on RxList: 2/2/2006
This monograph has been modified to include the generic and brand name in many instances.