Impetigo (pronounced im-puh-TIE-go) is a contagious, superficial infection of the skin caused by staphylococcus (Staph) and streptococcus (Strep) bacteria. Impetigo is more common in children (especially 2- to 5-year-olds) than in adults. Impetigo is most likely to occur in warm and humid environments and is most commonly spread by close contact (such as family members).
There are two kinds of impetigo:
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MAXIPIME®
(cefepime hydrochloride, USP) for Injection
For Intravenous or Intramuscular Use
To reduce the development of drug-resistant bacteria and maintain the effectiveness of MAXIPIME® (cefepime hydrochloride for injection) and other antibacterial drugs, MAXIPIME (cefepime hydrochloride for injection) should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.
MAXIPIME (cefepime hydrochloride, USP) is a semi-synthetic, broad spectrum, cephalosporin antibiotic for parenteral administration. The chemical name is 1-[[(6R,7R)-7-[2-(2-amino-4-thiazolyl)-glyoxylamido]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-en-3-yl]methyl]-1-methylpyrrolidinium chloride, 72-(Z)-(O-methyloxime), monohydrochloride, monohydrate, which corresponds to the following structural formula:
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Cefepime hydrochloride is a white to pale yellow powder. Cefepime hydrochloride contains the equivalent of not less than 825 mcg and not more than 911 mcg of cefepime (C19H24N6O5S2) per mg, calculated on an anhydrous basis. It is highly soluble in water.
MAXIPIME (cefepime hydrochloride for injection) for Injection is supplied for intramuscular or intravenous administration in strengths equivalent to 500 mg, 1 g, and 2 g of cefepime. (See DOSAGE AND ADMINISTRATION.) MAXIPIME (cefepime hydrochloride for injection) is a sterile, dry mixture of cefepime hydrochloride and L-arginine. It contains the equivalent of not less than 90 percent and not more than 115 percent of the labeled amount of cefepime (C19H24N6O5S2). The L-arginine, at an approximate concentration of 725 mg/g of cefepime, is added to control the pH of the constituted solution at 4.0–6.0. Freshly constituted solutions of MAXIPIME (cefepime hydrochloride for injection) will range in color from colorless to amber.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
Read All Potential Side Effects and See Pictures of Maxipime »
Before using cefepime, tell your doctor or pharmacist if you are allergic to it; or to other cephalosporins; or to penicillins; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, stomach/intestinal diseases (e.g., colitis).
Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, elderly people may be at greater risk for side effects while using this drug.
Tell your doctor if you are pregnant before using this medication.
This medication passes into breast milk and may have...
Last reviewed on RxList: 10/13/2009
This monograph has been modified to include the generic and brand name in many instances.
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