April 29, 2017
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(neomycin and polymyxin B sulfates and dexamethasone ophthalmic) Ointment


MAXITROL® (neomycin and polymyxin B sulfates and dexamethasone ophthalmic ointment) is a multiple dose anti-infective steroid combination in sterile ointment form for topical application.

The chemical structure for the active ingredient Neomycin Sulfate is:

Neomycin Sulfate - Structural Formula Illustration

Neomycin B (R1=H, R2=CH2NH2)

Neomycin C (R1=CH2NH2, R2=H)

The chemical structure for the active ingredient Polymyxin B Sulfate is:

Polymyxin B Sulfate - Structural Formula Illustration

Polymyxin B1 (R=CH3)

Polymyxin B2 (R=H)

DAB = α, γ - diaminobutyric acid

The chemical structure for the active ingredient Dexamethasone is:

Dexamethasone - Structural Formula Illustration

Established Name: Dexamethasone

Chemical Name: Pregna-1, 4-diene-3, 20-dione,9-fluoro-11,17, 21-trihydroxy-16-methyl-, (11β, 16α)-.

Each Gram Contains

Active: neomycin sulfate equivalent to neomycin 3.5 mg, polymyxin B sulfate 10,000 units, dexamethasone 0.1%. Preservatives: methylparaben 0.05%, propylparaben 0.01%. Inactives: white petrolatum, anhydrous liquid lanolin.

What are the possible side effects of neomycin, polymyxin B and dexamethasone ophthalmic (Maxitrol, Ocu-Trol, Poly-Dex)?

Serious side effects are not expected with this medication.

Some burning, stinging, irritation, itching, redness, blurred vision, eyelid itching, eyelid swelling, or sensitivity to light may occur.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at...

Read All Potential Side Effects and See Pictures of Maxitrol »

What are the precautions when taking neomycin, polymyxin b and dexamethasone ophthalmic (Maxitrol)?

Before using this medication, tell your doctor or pharmacist if you are allergic to neomycin, polymyxin, or dexamethasone; or to aminoglycoside antibiotics (e.g., gentamicin, tobramycin); or to corticosteroids (e.g., hydrocortisone, prednisone); or if you have any other allergies. This product may contain inactive ingredients (such as preservatives like benzalkonium chloride), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: other eye problems (e.g., glaucoma).

After you apply this drug, your vision may become temporarily unstable. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you...

Read All Potential Precautions of Maxitrol »

Last reviewed on RxList: 4/21/2017
This monograph has been modified to include the generic and brand name in many instances.

Maxitrol - User Reviews

Maxitrol User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Maxitrol sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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