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Medrol

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Medrol

Medrol®
(methylprednisolone) Tablets, USP

DRUG DESCRIPTION

MEDROL Tablets contain methylprednisolone which is a glucocorticoid. Glucocorticoids are adrenocortical steroids, both naturally occurring and synthetic, which are readily absorbed from the gastrointestinal tract. Methylprednisolone occurs as a white to practically white, odorless, crystalline powder. It is sparingly soluble in alcohol, in dioxane, and in methanol, slightly soluble in acetone, and in chloroform, and very slightly soluble in ether. It is practically insoluble in water.

The chemical name for methylprednisolone is pregna - 1,4 - diene - 3,20-dione, 11, 17, 21-trihydroxy-6-methyl-, (6α, 11β)-and the molecular weight is 374.48. The structural for-mula is represented below:

Medrol® (methylprednisolone) structural formula illustration

Each MEDROL (methylprednisolone) Tablet for oral administration contains 2 mg, 4 mg, 8 mg, 16 mg or 32 mg of methylprednisolone.
Inactive ingredients:

2 mg
Calcium Stearate
Corn Starch
Erythrosine Sodium
Lactose
Mineral Oil
Sorbic Acid
Sucrose

4 and 16 mg
Calcium Stearate
Corn Starch
Lactose
Mineral Oil
Sorbic Acid
Sucrose

8 and 32 mg
Calcium Stearate
Corn Starch
F D & C Yellow No. 6
Lactose
Mineral Oil
Sorbic Acid
Sucrose

What are the possible side effects of methylprednisolone (Medrol, Medrol Dosepak, MethylPREDNISolone Dose Pack)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • problems with your vision;
  • swelling, rapid weight gain, feeling short of breath;
  • severe depression, unusual thoughts or behavior, seizure (convulsions);
  • bloody or tarry stools, coughing up blood;
  • pancreatitis (severe pain in your upper stomach spreading to your...

Read All Potential Side Effects and See Pictures of Medrol »

What are the precautions when taking methylprednisolone (Medrol)?

Before taking methylprednisolone, tell your doctor or pharmacist if you are allergic to it; or to prednisone; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: bleeding problems, blood clots, brittle bones (osteoporosis), diabetes, eye diseases (such as cataracts, glaucoma, herpes infection of the eye), heart problems (such as recent heart attack, congestive heart failure), high blood pressure, current/past infections (such as those caused by tuberculosis, threadworm, herpes, fungus), kidney disease, liver disease, mental/mood conditions (such as psychosis,...

Read All Potential Precautions of Medrol »

Last reviewed on RxList: 10/4/2010
This monograph has been modified to include the generic and brand name in many instances.

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Medrol - User Reviews

Medrol User Reviews

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Here is a collection of user reviews for the medication Medrol sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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