Medrol (Methylprednisolone) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 3, 2012

Medrol

Asthma »

Myths, facts, and statistics about asthma

Before we present the typical symptoms of asthma, we should dispel some common myths about this condition. This is best achieved by conducting a short true or false quiz.

T or F - Asthma is "all in the mind."
T or F - You will "grow out of it."
T or F - Asthma can be cured, so it is not serious and nobody dies from it.
T or F - You are likely to develop asthma if someone in your family has it.
T or F - You can "catch" asthma from someone else who has it.
T or F - Moving to a different location, such as the desert, can cure asthma.
T or F - People with asthma should not exercise.
T or F - Asthma is best controlled when one has an asthma management plan designed by your doctor. This should include the medications used for quick relief as well as maintenance therapy.
T or F - Medications used to treat asthma are habit...

Read the Asthma article »

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Medrol®
(methylprednisolone) Tablets, USP

DRUG DESCRIPTION

MEDROL Tablets contain methylprednisolone which is a glucocorticoid. Glucocorticoids are adrenocortical steroids, both naturally occurring and synthetic, which are readily absorbed from the gastrointestinal tract. Methylprednisolone occurs as a white to practically white, odorless, crystalline powder. It is sparingly soluble in alcohol, in dioxane, and in methanol, slightly soluble in acetone, and in chloroform, and very slightly soluble in ether. It is practically insoluble in water.

The chemical name for methylprednisolone is pregna - 1,4 - diene - 3,20-dione, 11, 17, 21-trihydroxy-6-methyl-, (6α, 11β)-and the molecular weight is 374.48. The structural for-mula is represented below:

Medrol® (methylprednisolone) structural formula illustration

Each MEDROL (methylprednisolone) Tablet for oral administration contains 2 mg, 4 mg, 8 mg, 16 mg or 32 mg of methylprednisolone.
Inactive ingredients:

2 mg
Calcium Stearate
Corn Starch
Erythrosine Sodium
Lactose
Mineral Oil
Sorbic Acid
Sucrose

4 and 16 mg
Calcium Stearate
Corn Starch
Lactose
Mineral Oil
Sorbic Acid
Sucrose

8 and 32 mg
Calcium Stearate
Corn Starch
F D & C Yellow No. 6
Lactose
Mineral Oil
Sorbic Acid
Sucrose

What are the possible side effects of methylprednisolone (Medrol, Medrol Dosepak, MethylPREDNISolone Dose Pack)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

problems with your vision;
swelling, rapid weight gain, feeling short of breath;
severe depression, unusual thoughts or behavior, seizure (convulsions);
bloody or tarry stools, coughing up blood;

Read All Potential Side Effects and See Pictures of Medrol »

What are the precautions when taking methylprednisolone (Medrol)?

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: untreated active fungal infections.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: bleeding problems, history of blood clots, brittle bones (osteoporosis), high blood pressure, certain heart problems (such as congestive heart failure), diabetes, certain eye diseases (such as cataracts, herpes infection,...

Read All Potential Precautions of Medrol »

Last reviewed on RxList: 10/4/2010
This monograph has been modified to include the generic and brand name in many instances.