Mefoxin

Drug Description
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MEFOXIN®
(cefoxitin) Injection

To reduce the development of drug-resistant bacteria and maintain the effectiveness of MEFOXIN* and other antibacterial drugs, MEFOXIN should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

DRUG DESCRIPTION

MEFOXIN (Cefoxitin for Injection) is a semi-synthetic, broad-spectrum cepha antibiotic sealed under nitrogen for intravenous administration. It is derived from cephamycin C, which is produced by Streptomyces lactamdurans. Its chemical name is sodium (6R,7S)-3-(hydroxymethyl)-7-methoxy-8-oxo-7- [2-(2-thienyl)acetamido]-5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylate carbamate (ester). The empirical formula is C16H16N3NaO7S2, and the structural formula is:

MEFOXIN (Cefoxitin) structural formula illustration

MEFOXIN contains approximately 53.8 mg (2.3 milliequivalents) of sodium per gram of cefoxitin activity. Solutions of MEFOXIN range from colorless to light amber in color. The pH of freshly constituted solutions usually ranges from 4.2 to 7.0.

Last updated on RxList: 10/2/2007


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