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Megestrol Acetate Tablets

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Megestrol Acetate Tablets

Megestrol Acetate Tablets

Megestrol Acetate Tablets Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Megestrol acetate is an antineoplastic (anticancer) and progestational drug used for the palliative treatment of advanced carcinoma of the breast or endometrium (i.e., recurrent, inoperable, or metastatic disease). It should not be used in lieu of currently accepted procedures such as surgery, radiation, or chemotherapy. This medication is available in generic form. Common side effects include weight gain, blood clots, heart failure, nausea and vomiting, edema, breakthrough menstrual bleeding, indigestion, tumor flare, high blood sugar, glucose intolerance, hair loss, high blood pressure, carpal tunnel syndrome, mood changes, hot flashes, weakness, lethargy, sweating, and rash.

The dose of megestrol acetate to treat breast cancer is 160 mg/day (40 mg four times daily). To treat endometrial carcinoma, the dose is 40 to 320 mg/day in divided doses. Megestrol acetate may interact with other drugs. Tell your doctor all medications and supplements you use. Megestrol acetate should not be used during pregnancy. It may harm a fetus. Because of the potential for adverse effects on the newborn, nursing should be discontinued if megestrol is required for treatment of cancer.

Our megestrol acetate Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Megestrol Acetate Tablets FDA Prescribing Information: Side Effects
(Adverse Reactions)

SIDE EFFECTS

Weight Gain

Weight gain is a frequent side effect of megestrol. This gain has been associated with increased appetite and is not necessarily associated with fluid retention.

Thromboembolic Phenomena

Thromboembolic phenomena including thrombophlebitis and pulmonary embolism (in some cases fatal) have been reported.

Glucocorticoid Effects

(See WARNINGS section.)

Heart failure, nausea and vomiting, edema, breakthrough menstrual bleeding, dyspnea, tumor flare (with or without hypercalcemia), hyperglycemia, glucose intolerance, alopecia, hypertension, carpal tunnel syndrome, mood changes, hot flashes, malaise, asthenia, lethargy, sweating and rash.

Read the entire FDA prescribing information for Megestrol Acetate Tablets (Megestrol Acetate Tablets) »

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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